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  • © 2008

Signal Transduction in the Cardiovascular System in Health and Disease

  • Contributions from internationally renowned researchers
  • A must-read book for scientists working in academia as well as pharmaceutical industry
  • Would be highly appreciated by students, as well as clinical researchers working in the area of cardiovascular diseases

Part of the book series: Advances in Biochemistry in Health and Disease (ABHD, volume 3)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xviii
  2. G-protein-Coupled Receptor Signaling

    1. Implication of G-proteins in Cardiovascular Disease

      • Madhu B. Anand-Srivastava
      Pages 3-26
    2. β-Adrenoceptor-Linked Signal Transduction Mechanisms in Congestive Heart Failure

      • Melissa R. Dent, Tushi Singal, Paramjit S. Tappia, Rajat Sethi, Naranjan S. Dhalla
      Pages 27-49
    3. Cardiac Gαs and Gαi Modulate Sympathetic Versus Parasympathetic Mechanisms in Hyperhomocysteinemia

      • Thomas P. Vacek, Karni S. Moshal, Naira Metreveli, Neetu Tyagi, Utpal Sen, Dorothea Rosenberger et al.
      Pages 51-66
    4. The Role of the Beta-Adrenergic Signal Transduction Pathway in Myocardial Protection

      • Johan Moolman, Erna Marais, Sonia Genade, Syanda Makaula, Amanda Lochner
      Pages 67-87
    5. Angiotensin II Signaling in Vascular Physiology and Pathophysiology

      • Niels Engberding, Kathy K. Griendling
      Pages 89-115
    6. Angiotensin II Signaling: Cell Growth and Apoptosis

      • Stephen W. Schaffer, Mahmood S. Mozaffari
      Pages 117-137
  3. Redox Signaling

    1. Thioredoxin Signaling in the Ischemic Heart

      • Dipak K. Das, Shyamal K. Goswami
      Pages 141-155
    2. Role of Hyperglycemia and Redox-Induced Signaling in Vascular Complications of Diabetes

      • Ashok K. Srivastava, Madhu B. Anand-Srivastava
      Pages 177-192
    3. Methylglyoxal and Insulin Resistance

      • Lingyun Wu
      Pages 193-208
  4. Growth Factor Signaling

    1. Regulatory Role of TGF-β in Cardiac Myofibroblast Function and Post-MI Cardiac Fibrosis: Key Roles of Smad7 and c-Ski

      • Ian M. C. Dixon, Baiqiu Wang, Kristen M. Bedosky, Ryan H. Cunnington, Sunil G. Rattan, Ahmed Almaqrhi
      Pages 249-266
    2. The Signaling Duel Between Virus and Host: Impact on Coxsackieviral Pathogenesis

      • Xiaoning Si, David Marchant, Decheng Yang, Bruce M. McManus, Honglin Luo
      Pages 267-284
    3. VEGF Signaling: A Therapeutic Target for Cardiovascular Disease

      • Dhanya Chandrasekharan Rajalakshmi, Aghila Rani Koippallil Gopalakrishnan, Chandrasekharan Cheranellore Kartha
      Pages 301-326
  5. Calcium Signaling

    1. Ca2+/Calmodulin-Dependent Protein Kinase II Signaling in Vascular Smooth Muscle

      • Suzanne J. House, Melissa M. Zachar, Roman G. Ginnan, Dee Van Riper, Harold A. Singer
      Pages 339-355

About this book

Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders.

This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Editors and Affiliations

  • Department of Medicine, University of Montreal and Research Centre of the Centre Hospitalier de l’ Universite de Montreal, Montreal, Canada

    Ashok K. Srivastava

  • Department of Physiology Faculty of Medicine, University of Montreal, Montreal, Canada

    Madhu B. Anand-Srivastava

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access