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  • © 2005

Viral Membrane Proteins: Structure, Function, and Drug Design

  • First book in the new series Protein Reviews
  • Written by renowned leaders in the field, this volume summarizes the current structural and functional knowledge of membrane proteins encoded by viruses while at the same time addressing questions about the proteins as potential drug targets, thus providing the most comprehensive volume in this field of research

Part of the book series: Protein Reviews (PRON, volume 1)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xviii
  2. Membrane Proteins from Plant Viruses

    1. Front Matter

      Pages 1-1
    2. Membrane Proteins in Plant Viruses

      • Michael J. Adams, John F. Antoniw
      Pages 3-19
    3. Structure and Function of a Viral Encoded K+ Channel

      • Anna Moroni, James Van Etten, Gerhard Thiel
      Pages 21-32
  3. Fusion Proteins

    1. Front Matter

      Pages 33-33
    2. HIV gp41: A Viral Membrane Fusion Machine

      • Sergio G. Peisajovich, Yechiel Shai
      Pages 35-47
    3. Aspects of the Fusogenic Activity of Influenza Hemagglutinin Peptides by Molecular Dynamics Simulations

      • L. Vaccaro, K. J. Cross, S. A. Wharton, J. J. Skehel, F. Fraternali
      Pages 65-75
  4. Viral Ion Channels/viroporins

    1. Front Matter

      Pages 77-77
    2. Viral Proteins that Enhance Membrane Permeability

      • María Eugenia González, Luis Carrasco
      Pages 79-90
    3. FTIR Studies of Viral Ion Channels

      • Itamar Kass, Isaiah T. Arkin
      Pages 91-100
    4. The M2 Proteins of Influenza A and B Viruses are Single-Pass Proton Channels

      • Yajun Tang, Padmavati Venkataraman, Jared Knopman, Robert A. Lamb, Lawrence H. Pinto
      Pages 101-111
    5. Structure and Function of Vpu from HIV-1

      • S. J. Opella, S. H. Park, S. Lee, D. Jones, A. Nevzorov, M. Mesleh et al.
      Pages 147-163
    6. Defining Drug Interactions with the Viral Membrane Protein Vpu from HIV-1

      • V. Lemaitre, C. G. Kim, D. Fischer, Y. H. Lam, A. Watts, W. B. Fischer
      Pages 187-205
    7. Virus Ion Channels Formed by Vpu of HIV-1, the 6K Protein of Alphaviruses and NB of Influenza B Virus

      • Peter W. Gage, Gary Ewart, Julian Melton, Anita Premkumar
      Pages 207-231
    8. The Alphavirus 6K Protein

      • M. A. Sanz, V. Madan, J. L. Nieva, Luis Carrasco
      Pages 233-244

About this book

In Viral Membrane Proteins: Structure, Function, and Drug Design, Wolfgang Fischer summarizes the current structural and functional knowledge of membrane proteins encoded by viruses. In addition, contributors to the book address questions about proteins as potential drug targets. The range of information covered includes signal proteins, ion channels, and fusion proteins.

This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.

Editors and Affiliations

  • Department of Biochemistry, University of Oxford, UK

    Wolfgang B. Fischer

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access