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Recent Advances in Epilepsy Research

  • Book
  • © 2004

Overview

Editors:
  1. Devin K. Binder

    1. Department of Neurological Surgery, Moffitt Hospital, University of California at San Francisco, San Francisco, USA

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  2. Helen E. Scharfman

    1. Center for Neural Recovery and Rehabilitation Research, New York State Department of Health, Helen Hayes Hospital, West Haverstraw, USA
      Departments of Pharmacology and Neurology, Columbia University, New York, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 548)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Genetic Approaches to Studying Mouse Models of Human Seizure Disorders

    • Yan Yang, Wayne N. Frankel
    Pages 1-11

  3. Integrins, Synaptic Plasticity and Epileptogenesis

    • Christine M. Gall, Gary Lynch
    Pages 12-33

  4. The Role of BDNF in Epilepsy and Other Diseases of the Mature Nervous System

    • Devin K. Binder
    Pages 34-56

  5. Vascular Endothelial Growth Factor (VEGF) in Seizures:

    • Susan D. Croll, Jeffrey H. Goodman, Helen E. Scharfman
    Pages 57-68

  6. Plasticity Mechanisms Underlying mGluR-Induced Epileptogenesis

    • Robert K. S. Wong, Shih-Chieh Chuang, Riccardo Bianchi
    Pages 69-75

  7. Role of the GABA Transporter in Epilepsy

    • George B. Richerson, Yuanming Wu
    Pages 76-91

  8. GABA and Its Receptors in Epilepsy

    • Günther Sperk, Sabine Furtinger, Christoph Schwarzer, Susanne Pirker
    Pages 92-103

  9. Role of the Depolarizing GABA Response in Epilepsy

    • Kevin J. Staley
    Pages 104-109

  10. Gap Junctions, Fast Oscillations and the Initiation of Seizures

    • Roger D. Traub, Hillary Michelson-Law, Andrea E. J. Bibbig, Eberhard H. Buhl, Miles A. Whittington
    Pages 110-122

  11. Functional Role of Proinflammatory and Anti-Inflammatory Cytokines in Seizures

    • Annamaria Vezzani, Daniela Moneta, Cristina Richichi, Carlo Perego, Maria G. De Simoni
    Pages 123-133

  12. Using the Immune System to Target Epilepsy

    • Deborah Young, Matthew J. During
    Pages 134-144

  13. Cortical Dysplasia and Epilepsy: Animal Models

    • Philip A. Schwartzkroin, Steven N. Roper, H. Jurgen Wenzel
    Pages 145-174

  14. Malformations of Cortical Development: Molecular Pathogenesis and Experimental Strategies

    • Peter B. Crino
    Pages 175-191

  15. Functional Implications of Seizure-Induced Neurogenesis

    • Helen E. Scharfman
    Pages 192-212

  16. Febrile Seizures and Mechanisms of Epileptogenesis: Insights from an Animal Model

    • Roland A. Bender, Celine Dubé, Tallie Z. Baram
    Pages 213-225

  17. The Tetanus Toxin Model of Chronic Epilepsy

    • Timothy A. Benke, John Swann
    Pages 226-238

  18. Brain Stimulation As a Therapy for Epilepsy

    • Jeffrey H. Goodman
    Pages 239-247
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Keywords

About this book

Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented in vitro and in vivo electrophysiologic and phenotypic characterization. Recent Advances in Epilepsy Research sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry.
Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epilepsy, malformations of cortical development, neurogenesis, new animal models of epilepsy and the use of brain stimulation to treat epilepsy. This book should be of interest to a wide variety of audiences, including graduate students in neurobiology and related disciplines, neuroscientists, medical students, neurologists, neurosurgeons, and industry including pharmaceutical companies and medical device companies. There are many ideas in this book that will lead ingenious innovators in academia and industry to develop new and better therapies.

Editors and Affiliations

  • Department of Neurological Surgery, Moffitt Hospital, University of California at San Francisco, San Francisco, USA

    Devin K. Binder

  • Center for Neural Recovery and Rehabilitation Research, New York State Department of Health, Helen Hayes Hospital, West Haverstraw, USA

    Helen E. Scharfman

  • Departments of Pharmacology and Neurology, Columbia University, New York, USA

    Helen E. Scharfman

Bibliographic Information

  • Book Title: Recent Advances in Epilepsy Research

  • Editors: Devin K. Binder, Helen E. Scharfman

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4757-6376-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2004

  • Hardcover ISBN: 978-0-306-47860-4Published: 24 June 2004

  • Softcover ISBN: 978-1-4419-3418-5Published: 06 December 2010

  • eBook ISBN: 978-1-4757-6376-8Published: 14 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVIII, 248

  • Topics: Neurosciences, Neurology, Pharmacology/Toxicology

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