Advances in Experimental Medicine and Biology

Lymphocyte Activation and Immune Regulation IX

Homeostasis and Lymphocyte Traffic

Editors: Gupta, Sudhir, Butcher, Eugene, Paul, William E. (Eds.)

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About this book

This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented.
Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans.
Novel methods of visualization of immune cells and immune systems are reviewed in Section III.

Table of contents (26 chapters)

  • Lymphocyte Development in Neonatal and Adult C-Kit-Deficient (C-Kitw/w) Mice

    Waskow, Claudia (et al.)

    Pages 1-10

  • Development of Antigen-Specific Helper T Cell Responses in Vivo

    McHeyzer-Williams, Louise (et al.)

    Pages 11-20

  • Bcl-6 Uncouples B Lymphocyte Proliferation from Differentiation

    Fearon, Douglas T. (et al.)

    Pages 21-28

  • The Role of Vav Proteins in B Cell Responses

    Turner, Martin

    Pages 29-34

  • Traffic Patterns of B Cells and Plasma Cells

    Cyster, Jason G. (et al.)

    Pages 35-41

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4615-0757-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-0-306-47395-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-1-4613-5226-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Lymphocyte Activation and Immune Regulation IX
Book Subtitle
Homeostasis and Lymphocyte Traffic
Editors
  • Sudhir Gupta
  • Eugene Butcher
  • William E. Paul
Series Title
Advances in Experimental Medicine and Biology
Series Volume
512
Copyright
2002
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-0757-4
DOI
10.1007/978-1-4615-0757-4
Hardcover ISBN
978-0-306-47395-1
Softcover ISBN
978-1-4613-5226-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
IX, 212
Topics