Pharmaceutical Biotechnology

Rational Design of Stable Protein Formulations

Theory and Practice

Editors: Carpenter, John F., Manning, Mark C. (Eds.)

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eBook $199.00
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  • ISBN 978-1-4615-0557-0
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About this book

Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view.

This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.

Table of contents (8 chapters)

  • Practical Approaches to Protein Formulation Development

    Chang, Byeong S. (et al.)

    Pages 1-25

  • Recombinant Production of Native Proteins from Escherichia coli

    Arakawa, Tsutomu (et al.)

    Pages 27-60

  • Physical Stabilization of Proteins in Aqueous Solution

    Kendrick, Brent S. (et al.)

    Pages 61-84

  • Effects of Conformation on the Chemical Stability of Pharmaceutically Relevant Polypeptides

    Meyer, Jeffrey D. (et al.)

    Pages 85-107

  • Rational Design of Stable Lyophilized Protein Formulations: Theory and Practice

    Carpenter, John F. (et al.)

    Pages 109-133

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-1-4615-0557-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-306-46741-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4613-5131-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Rational Design of Stable Protein Formulations
Book Subtitle
Theory and Practice
Editors
  • John F. Carpenter
  • Mark C. Manning
Series Title
Pharmaceutical Biotechnology
Series Volume
13
Copyright
2002
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-0557-0
DOI
10.1007/978-1-4615-0557-0
Hardcover ISBN
978-0-306-46741-7
Softcover ISBN
978-1-4613-5131-3
Series ISSN
1078-0467
Edition Number
1
Number of Pages
XVII, 206
Topics