Advances in Experimental Medicine and Biology

Mechanisms of Lymphocyte Activation and Immune Regulation VIII

Autoimmunity 2000 and Beyond

Editors: Gupta, Sudhir (Ed.)

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About this book

Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies.
This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.

Table of contents (13 chapters)

  • Delineation of the Pathogenesis of Systemic Lupus Erythematosus by Using Murine Models

    Liu, Kui (et al.)

    Pages 1-6

  • Factors Contributing to Autoimmune Disease

    Garza, Kristine M. (et al.)

    Pages 7-19

  • Control of Autoimmunity by Regulatory T Cells

    Shevach, Ethan M. (et al.)

    Pages 21-32

  • Autoimmunity, Self-Tolerance and Immune Homeostasis: From Whole Animal Phenotypes to Molecular Pathways

    Goodnow, Christopher C. (et al.)

    Pages 33-40

  • Peripheral Tolerance and Organ Specific Autoimmunity

    Boehmer, Harald (et al.)

    Pages 41-48

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-4615-1243-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-0-306-46570-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4613-5458-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mechanisms of Lymphocyte Activation and Immune Regulation VIII
Book Subtitle
Autoimmunity 2000 and Beyond
Editors
  • Sudhir Gupta
Series Title
Advances in Experimental Medicine and Biology
Series Volume
490
Copyright
2001
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-1243-1
DOI
10.1007/978-1-4615-1243-1
Hardcover ISBN
978-0-306-46570-3
Softcover ISBN
978-1-4613-5458-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 136
Topics