Advances in Ocular Toxicology

Editors: Green, K., Edelhauser, H.F., Hull, D.S., Potter, D.E., Tripathi, R.C. (Eds.)

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About this book

This volume represents the proceedings of the Fifth Congress of the International Society of Ocular Toxicology (ISOT), which was held at the Grove Park Inn and Resort in Asheville, North Carolina, October 13-17, 1996. We are delighted to present this volume to the ophthalmic community, especially those with a significant interest in ocular toxicol­ ogy. The Fifth Congress was developed around themes relating to ocular drug metabolism, the ocular pathophysiological effects of nitric oxide, government issues relating to the use of alternative methods for toxicity testing, and a workshop that encompassed comparisons of both in vitro versus in vivo models as well as different animal models. The outcome of this congress, embodied in this volume, is a contribution to the methodologies currently employed or under development and to various drug or physical effects on different ocular tissues. While the focus of this proceedings is on ocular effects of drugs or other materials, many of the contributions deal with topics that have a much broader interest. The workshop concerning the use of different model systems and the choice of the best animal model for drug testing covers a wide range of interests that ex­ tends far beyond specific ocular effects. This is especially true in the area of alternative methods and in the choice of the best animal model for examination of different disease entities.

Table of contents (25 chapters)

  • Welcome and Opening of Congress

    Green, Keith

    Pages 1-2

  • Cytochrome P450 and Arachidonic Acid Metabolism in the Corneal Epithelium

    Schwartzman, Michal Laniado

    Pages 3-20

  • The Effects of 12(R)Hete and Its Metabolite 8(R)HHDTre on Corneal Endothelial Function

    Edelhauser, Henry F. (et al.)

    Pages 21-26

  • Protein-Thiol Mixed Disulfides and Thioltransferase in the Lens

    Lou, Marjorie F.

    Pages 27-46

  • Corneal Lesions in Beagle Dogs Given Oral 5-Ethynyluracil Followed by 5-Fluorouracil

    Peiffer, Robert L. (et al.)

    Pages 47-53

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4615-5937-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-306-45614-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4613-7720-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Advances in Ocular Toxicology
Editors
  • Keith Green
  • Henry F. Edelhauser
  • David S. Hull
  • David E. Potter
  • Ramesh C. Tripathi
Copyright
1997
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4615-5937-5
DOI
10.1007/978-1-4615-5937-5
Hardcover ISBN
978-0-306-45614-5
Softcover ISBN
978-1-4613-7720-7
Edition Number
1
Number of Pages
XV, 276
Topics