Enzymes of the Cholinesterase Family

Editors: Balasubramanian, A.S., Doctor, B.P., Quinn, D.M., Taylor, P. (Eds.)

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About this book

The Fifth International Meeting on Cholinesterases convened in Madras, India, in September of 1994. The long and rich history and culture of India provided an excellent setting for the meeting. More than 120 delegates from Asia, Australia, Europe and North America heard 54 oral presentations and viewed 54 posters on current research on enzymes of the cholinesterase family. The aim of this book is to compile the presentations of the Fifth International Meeting on Cholinesterases into a volume that describes recent investigations on the structure and catalytic function of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and related enzymes, as well as studies on the molecular and cellular biology of these enzymes and the genes which encode them. Cholinesterases enjoy a long and storied history in diverse areas. In basic biochemical research, AChE is one of the best studied, though yet enigmatic, of enzymes. The efficient catalytic function of this enzyme presents the biochemist with a fundamental challenge in understanding the relationship between structure and function. AChE and BuChE belong to a family of proteins, the alB hydrolase fold family, whose constituents evolutionarily diverged from a common ancestor. Proteins in this family have a wide range of physiological functions. In commerce, AChE is a prime target for agricultural insect control, and for the development of therapeutic agents for Alzheimer's disease.

Table of contents (103 chapters)

  • Antisense Oligonucleotides Suppressing Expression of Cholinesterase Genes Modulate Hematopoiesis in Vivo and ex Vivo

    Soreq, Hermona (et al.)

    Pages 1-6

  • Properties of Class a Acetylcholinesterase, the Enzyme Encoded by ACE-1 in Caenorhabditis elegans

    Arpagaus, Martine (et al.)

    Pages 7-13

  • Ligand Specificity and Gene Expression in the Cholinergic Synapse

    Taylor, Palmer (et al.)

    Pages 15-21

  • Butyrylcholinesterase Transcription Start Site and Promoter

    Jbilo, Omar (et al.)

    Pages 23-28

  • The C-Terminal Alternative Regions of Acetylcholinesterase

    Massoulié, Jean (et al.)

    Pages 29-36

Buy this book

eBook $299.00
price for USA (gross)
  • ISBN 978-1-4899-1051-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $389.00
price for USA
  • ISBN 978-0-306-45135-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $379.00
price for USA
  • ISBN 978-1-4899-1053-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Enzymes of the Cholinesterase Family
Editors
  • A.S. Balasubramanian
  • Bhupendra P. Doctor
  • Daniel M. Quinn
  • Palmer Taylor
Copyright
1995
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4899-1051-6
DOI
10.1007/978-1-4899-1051-6
Hardcover ISBN
978-0-306-45135-5
Softcover ISBN
978-1-4899-1053-0
Edition Number
1
Number of Pages
XVII, 534
Topics