Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors

Authors: Leroith, Derek, Raizada, Mohan K.

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About this book

An essential element in the development and functional integrity of all organisms is intercellular communication. This is achieved by the secretion of soluble messenger molecules which subsequently interact with receptor-effector pathways in the responsive cells. Hormones are traditionally defined as chemical messengers synthesized by endocrine glands. Unlike hormones produced by endocrine glands, growth factors are hormone-related substances produced by many tissues and play an important role in controlling growth and development. While the exact physiological roles of growth factors have yet to be elucidated, they play important roles in the regulation of cellular proliferation and/or differentiation during ontogenesis, growth and differentiation. During recent years there has been a substantial increase in research related to peptide growth factors, their receptors, and modes of action. With the discovery and characterization of numerous growth factors, it became clear that these growth factors had multiple features in common with classic hormones as well as with oncogenes. Furthermore, there are distinct families of growth factors based either on structural or functional similarities.

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  • Hormonal Feedback Regulation of Brain IGF-I and IGF-II Gene Expression

    Teresa L. Wood, Michael Berelowitz, Jeffrey F. McKelvy

    Pages 209-217

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Buy this book

eBook $69.99 net
( price for USA )
  • ISBN 978-1-4684-5685-1
  • digitally watermarked, no DRM
  • included format: PDF
  • eBooks can be used on all Reading Devices
Hardcover $99.00 net
( price for USA )
  • ISBN 978-0-306-43254-5
  • free shipping for individuals worldwide
  • The book title is in reprint. You can already preorder it.
Softcover $99.00 net
( price for USA )
  • ISBN 978-1-4684-5687-5
  • free shipping for individuals worldwide
  • usually dispatched within 3 to 5 business days

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Bibliographic Information

Bibliographic Information
Book Title
Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors
Copyright
1989
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4684-5685-1
DOI
10.1007/978-1-4684-5685-1
Hardcover ISBN
978-0-306-43254-5
Softcover ISBN
978-1-4684-5687-5
Edition Number
1
Topics