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  • Book
  • © 2017

Notch Signaling

Immunity and Cancer

Editors:

  1. Koji Yasutomo

    1. Graduate School of Medicine, Tokushima University , Kuramoto, Japan

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  • Covers all areas of Notch functions in immune cells and tumorigenesis

  • Provides coverage of controversial issues, further facilitating research in this field

  • Includes detailed descriptions of the relationship of Notch signaling to human diseases

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-vii
    PDF

  2. Immunology

    1. Front Matter

      Pages 1-1
      PDF

    2. Notch Ligands for Lymphocyte Development

      • Katsuto Hozumi
      Pages 3-20

    3. Notch Controls the Differentiation and Function of Cytotoxic CD8 T Cells

      • Yoichi Maekawa, Takahide Ikeda, Piyarat Srinontong
      Pages 21-33

    4. Notch and Myeloid Cells

      • Chieko Ishifune, Koji Yasutomo
      Pages 35-55

    5. Taking CD4 T Cells Up a Notch

      • Christina Helbig, Derk Amsen
      Pages 57-75

  3. Cancer

    1. Front Matter

      Pages 77-77
      PDF

    2. NOTCH in Malignant Lymphoma

      • Shigeru Chiba
      Pages 79-92

    3. The Two Faces of Notch in Solid Cancers

      • Craig S. Nowell, Freddy Radtke
      Pages 93-104
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About this book

This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation or development as well as tumorigenesis of cells. Although there are still many controversial issues regarding the functions or regulatory mechanism of Notch, it is important to summarize all data together in one volume to help facilitate this research area. Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors. Therefore, this book covering the broad area of Notch in immunology and tumorigenesis will be attractive to many researchers including faculty members and postdoctoral fellows in academia and researchers in the pharmaceutical industry.
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Keywords

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Editors and Affiliations

  • Graduate School of Medicine, Tokushima University , Kuramoto, Japan

    Koji Yasutomo

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About the editor

Koji Yasutomo, M.D., Ph.D.
Department of Immunology and Parasitology, Graduate School of Medicine
Tokushima University
Tokushima, Japan

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Bibliographic Information

  • Book Title: Notch Signaling

  • Book Subtitle: Immunity and Cancer

  • Editors: Koji Yasutomo

  • DOI: https://doi.org/10.1007/978-981-10-4971-2

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2017

  • Hardcover ISBN: 978-981-10-4970-5Published: 18 August 2017

  • Softcover ISBN: 978-981-13-5280-5Published: 12 December 2018

  • eBook ISBN: 978-981-10-4971-2Published: 02 August 2017

  • Edition Number: 1

  • Number of Pages: VII, 104

  • Number of Illustrations: 3 b/w illustrations, 12 illustrations in colour

  • Topics: Immunology, Cancer Research

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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