Mechanical Ventilation in Critically Ill Cancer Patients

1. Front Matter

   Pages i-xi

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2. Background and Therapeutic Procedures in Critically Ill Cancer Patients

   1. Front Matter

      Pages 1-1

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   2. Epidemiology of Mechanical Ventilation and Acute Respiratory Failure in Cancer Patients

      • Dulce Apolinário

      Pages 3-7

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   3. Breathlessness in Advanced Cancer Patients: Protocols and Recommendations

      • Manuel Sánchez Cánovas, Juan Gutiérrez Mejía, Alberto Carmona Bayonas, Paula Jiménez-Fonseca

      Pages 9-20

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   4. Acute Respiratory Failure in Patients with Hematologic and Solid Malignancies: Global Approach

      • Sakshi Sethi, Stephen M. Pastores

      Pages 21-31

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   5. Radiation Therapy: Impact on Lung Function and Acute Respiratory Failure

      • Athanasia Proklou, Eleni Diamantaki, Emmanouil Pediaditis, Eumorfia Kondili

      Pages 33-39

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   6. Radiation Pneumonitis and Noninvasive Ventilation

      • Erica Altschul, Shalin Patel, Bushra Mina

      Pages 41-46

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   7. Blood Marrow Transplantation

      • Riccardo Boncompagni, Adriano Peris

      Pages 47-57

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   8. Ventilatory Approach in Upper Airway/Neck Cancer Patients with Respiratory Failure

      • Bushra Mina, Khalid Gafoor, Oki Ishikawa

      Pages 59-73

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   9. Psychological Aspects of Critically Ill Cancer

      • Zehra Hatipoğlu, Ayten Bolukbası, Dilek Ozcengiz

      Pages 75-81

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   10. Upper Acute Respiratory Failure in Neck Cancer

       • Nilgün Alpay, Mediha Turktan, Dilek Ozcengiz

       Pages 83-90

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   11. Acute Respiratory Failure Before ICU Admission: A Practical Approach

       • Eleni Diamantaki, Athanasia Proklou, Emmanouil Pediaditis, Vasilis Amargianitakis, Eumorfia Kondili

       Pages 91-102

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   12. Acute Myeloid Leukemia and Acute Respiratory Failure: Early Diagnosis and a Practical Approach

       • Gulsah Karaoren, Sibel Serin

       Pages 103-112

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   13. Cardiac Disease in Hematologic Cancer and Acute Respiratory Failure-General Considerations

       • Mina Bushra, Belete Habtamu, Sharma Sanjeev

       Pages 113-121

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   14. Cardiac Diseases in Hematology Cancer and Acute Respiratory Failure: Ventilatory Approach

       • Giuseppe Fiorentino, Antonio M. Esquinas, Anna Annunziata

       Pages 123-129

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   15. Oxygen Therapy and Ventilatory Approach in Elderly Cancer Patients: Key Practice Recommendations

       • Carmen M. Hernandez-Cardenas

       Pages 131-134

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3. Invasive and Non-Invasive Mechanical Ventilation

   1. Front Matter

      Pages 135-135

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   2. Rationale and Overview

      • Ravinder Bhanot, Abdulrazak Alchakaki, Jasleen Kaur, Ayman O. Soubani

      Pages 137-155

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   3. Invasive and Interventional Procedures

      • Fayez Kheir, Adnan Majid

      Pages 157-175

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   4. Modes of Mechanical Ventilation

      • Eduardo Mireles-Cabodevila, Abhijit Duggal, Robert L. Chatburn

      Pages 177-188

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This book aims to equip the reader to make optimal decisions on the use of mechanical ventilatory support in critically ill cancer patients with acute respiratory failure (ARF) and to implement the different strategies effectively. Detailed information is provided on the rationale for invasive and non-invasive ventilation, the different modes of ventilation, indications and contraindications, prognostic factors, and outcomes. The role of postoperative mechanical ventilation following various forms of surgery is extensively addressed, and key aspects of withdrawal from ventilatory support are discussed. Attention is also devoted to mechanical ventilation in the palliative care context. The concluding part of the book focuses on healthcare resource utilization and organizational support in cancer critical care. ARF is the most common reason for hospital and intensive care admission among oncological patients, and there is growing evidence that outcome following mechanical ventilation is improving. Readers will find this book to be an invaluable aid when selecting and executing a strategy for management of ARF in individual cancer patients.

• Acute respiratory failure
• Invasive mechanical ventilation
• Non-invasive mechanical ventilation
• Nasal high-flow therapy
• Postoperative mechanical ventilation
• Weaning from mechanical ventilation
• Indications for mechanical ventilation
• Contraindications to mechanical ventilation
• Outcomes after mechanical ventilation
• Palliative ventilatory support
• Solid tumors

“This book is devoted to the identification and management of respiratory complications in critically ill cancer patients. … Critical care providers encountering patients with advanced malignancy and multimodal therapy are an appropriate audience for this international work. … This book provides effective background on mechanical pulmonary support and the challenges of oncology patients.” (David J. Dries, Doody's Book Reviews, April, 2018)

• Intensive Care and Non Invasive Ventilatory Unit, Hospital Morales Meseguer, Murcia, Spain

  Antonio M. Esquinas

• Division of Anesthesiology and Critical Care, The University of Texas M.D. Anderson Cancer Center, Houston, USA

  S. Egbert Pravinkumar

• Wayne State University School of Medicine, Detroit, USA

  AYMAN O. SOUBANI

Antonio M. Esquinas, MD, PhD, is a member of staff on the Intensive Care Unit and Non-invasive Ventilatory Unit at Hospital General Universitario Morales Meseguer, Murcia, Spain. Prior to taking up this position in January 2013, he worked in the Departments of Anesthesiology, Critical Care, and Pain Medicine at Sapienza University of Rome, Italy. Dr. Esquinas is a Fellow of the College of Chest Physicians and an International Fellow of the American Association of Respiratory Care. He is Director of the International School of Non-invasive Mechanical Ventilation and President of the International Association of NIV and the Ibero-American  Association of  Bioethics in NIV. He is the author of well over 700 scientific publications, including almost 400 articles and 32 books.



S. Egbert Pravinkumar, MD, FRCP, EDIC, is Professor and Associate Medical Director, Department of Critical Care, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Dr. Pravinkumar completed his medical degree at Stanley Medical College and University Hospital, University of Madras, Madras, India and subsequently became a Member (1996) and then Fellow (2004) of the Royal College of Physicians of Ireland (Pulmonary Medicine/Internal Medicine). In 2006 he became a Fellow of the American College of Chest Physicians (Pulmonary/Critical Care Medicine). He is the author of 17 articles in peer-reviewed international journals.


Ayman O. Soubani, MD, is Professor of Medicine at Wayne State University School of Medicine, Detroit, MI, USA. He is Service Chief of the Pulmonary and Critical Care Section at Karmanos Cancer Center in Detroit and
Medical Director, Medical ICU, Harper University Hospital, Detroit. Dr. Soubani has appeared in both Best Doctors of America and America’s Top Doctors. He holds various professional appointments and is a past president of The Michigan Thoracic Society. Dr. Soubani is a member of the editorial boards of Respiration and The Open Transplantation Journal, and a reviewer for numerous journals. He is the author of 84 peer-reviewed journal articles.

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