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  • © 2019

Pathology of Graft vs. Host Disease

A Case Based Teaching Guide

  • Richly illustrated with comparative gross and histologic pictures of GVHD.

  • Provides a case based teaching primer.

  • Written by experts in their fields.

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi
  2. Evolutions in the Clinical Management of GVHD

    • Cecilia C. S. Yeung, H. Joachim Deeg
    Pages 11-20
  3. Early GVHD with Follicular Rash

    • Cecilia C. S. Yeung, Thanh T. Dinh, Howard M. Shulman
    Pages 21-34
  4. The Basic Sequence of Injury in Acute Skin GVHD

    • Teresa S. Hyun, Shiva Khoobyari, Oliver H. Chang
    Pages 35-45
  5. Leukemia Cutis and Hematologic Malignancies with Cutaneous Manifestation

    • Adam James Robin, Cecilia C. S. Yeung
    Pages 47-54
  6. Lichenoid Inflammatory Phase of Chronic Skin GVHD

    • Oliver H. Chang, Marie E. Perrone, Adam James Robin, Howard M. Shulman
    Pages 55-68
  7. Cutaneous Chronic GVHD: Sclerodermatous and Morpheic Variants

    • Teresa S. Hyun, Howard M. Shulman
    Pages 69-83
  8. Early Changes of Gut GVHD: Differential Diagnosis and Criteria for Crypt Cell Apoptosis

    • Cecilia C. S. Yeung, David W. Woolston, Howard M. Shulman
    Pages 85-95
  9. Persistent Gastrointestinal GVHD: The Application and Utility of Histologic Grading Schemes

    • Howard M. Shulman, David W. Woolston, David Myerson
    Pages 97-111
  10. Pathobiology of Fatal Gastrointestinal GVHD

    • Howard M. Shulman, David W. Woolston
    Pages 113-128
  11. Abdominal Pain and Diarrhea When It Is Not GVHD

    • David Myerson, Sahl Ali
    Pages 129-142
  12. Mucosal Chronic GVHD Affecting the Oral Pharyngeal, Esophageal, and Anogenital Regions

    • Howard M. Shulman, David M. Hockenbery, Cecilia C. S. Yeung
    Pages 143-156
  13. The Pathological Spectrum of Hepatic GVHD

    • Keith R. Loeb, David W. Woolston, Howard M. Shulman
    Pages 169-183
  14. Acute Hepatitic Onset of Liver GVHD Occurring 9 Months Post-transplant

    • Howard M. Shulman, Keith R. Loeb
    Pages 197-206
  15. GVHD Manifesting as Sicca Syndrome

    • Cecilia C. S. Yeung, Howard M. Shulman
    Pages 207-214
  16. Noninfectious Pulmonary Manifestation of GVHD: Bronchiolitis Obliterans Syndrome

    • Cecilia C. S. Yeung, Sahl Ali, Howard M. Shulman
    Pages 215-226
  17. Kidney Involvement in GVHD

    • Abbie Ruth Bauer, Laura S. Finn, Sangeeta R. Hingorani
    Pages 227-236

About this book

This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, pathologists and researchers with an interest in GVHD and its mimickers. The book reviews new data about risk factors affecting outcomes, pathologic features, and profiles the new WHO guidelines as well as current practices. The richly illustrated text covers the gamut of gross and histologic presentations of acute GVHD in skin, gut, liver, and additional organs affected by chronic GVHD.  An engaging aspect of this book is the format of patient based cases as the focus for the major chapters teaching points. The case presentations include both infectious and toxic complications that mimic GVHD, or displaying similar morphologies.  Recent up to date references on clinical investigations and pathogenesis make the reading and teaching resonant with the readers. 


Pathology of Graft vs. Host Disease will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging disease. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters were written by experienced transplant physicians with expertise in their fields. 

Editors and Affiliations

  • Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, USA

    Cecilia C. S. Yeung, Howard M. Shulman

About the editors



Cecilia CS Yeung
Fred Hutchinson Cancer Research Center
University of Washington
Seattle, WA
USA




Howard M. Shulman
Seattle Cancer Care Alliance
Seattle, WA
USA

Bibliographic Information

  • Book Title: Pathology of Graft vs. Host Disease

  • Book Subtitle: A Case Based Teaching Guide

  • Editors: Cecilia C. S. Yeung, Howard M. Shulman

  • DOI: https://doi.org/10.1007/978-3-319-42099-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-319-42098-1Published: 07 February 2019

  • eBook ISBN: 978-3-319-42099-8Published: 24 January 2019

  • Edition Number: 1

  • Number of Pages: XI, 251

  • Number of Illustrations: 1 b/w illustrations, 197 illustrations in colour

  • Topics: Pathology, Oncology

Buy it now

Buying options

eBook USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access