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  • © 2015

Biomaterials in Regenerative Medicine and the Immune System

  • Focus on biocompatibility

  • Comprehensive overview of the effects of biomaterials on the immune system

  • Emphasis on the immunological aspect of the subject?

  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-ix
  2. Role of Mesenchymal Stem Cells, Macrophages, and Biomaterials During Myocardial Repair

    • Isabella Pallotta, Emily A. Wrona, Bruce Sun, Donald O. Freytes
    Pages 1-15
  3. The Role of Macrophages in the Foreign Body Response to Implanted Biomaterials

    • Tony Yu, Valerie J. Tutwiler, Kara Spiller
    Pages 17-34
  4. Integrating Tissue Microenvironment with Scaffold Design to Promote Immune-Mediated Regeneration

    • Kaitlyn Sadtler, Franck Housseau, Drew Pardoll, Jennifer H. Elisseeff
    Pages 35-51
  5. Biomaterials-Based Strategies in Blood Substitutes

    • Anirban Sen Gupta
    Pages 113-137
  6. Biomaterials-Based Immunomodulation of Dendritic Cells

    • Evelyn Bracho-Sanchez, Jamal S. Lewis, Benjamin G. Keselowsky
    Pages 139-156
  7. Nanosystems for Immunotherapeutic Drug Delivery

    • Alex Schudel, Michael C. Bellavia, Susan N. Thomas
    Pages 157-170
  8. Biomaterial-Based Modulation of Cancer

    • Fnu Apoorva, Ankur Singh
    Pages 171-192
  9. Targeting Liposomes to Immune Cells

    • Matthew Levy, Deborah Palliser
    Pages 193-207
  10. Integrated Biomaterial Composites for Accelerated Wound Healing

    • Viness Pillay, Pradeep Kumar, Yahya E. Choonara
    Pages 209-223
  11. Adverse Effects of By-products from Polymers Used for Joint Replacement

    • Tzu-Hua Lin, Jukka Pajarinen, Florence Loi, Taishi Sato, Changchun Fan, Zhenyu Yao et al.
    Pages 225-256
  12. Back Matter

    Pages 279-280

About this book

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components.  As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

 

Editors and Affiliations

  • Albert Einstein College of Medicine, Bronx, USA

    Laura Santambrogio

About the editor

Dr. Santambrogio is Professor of Pathology, Microbiology and Immunology and Orthopedic Surgery at the Albert Einstein College of Medicine. She received her M.D. from the University of Perugia and her Ph.D. from the University of Padua in Italy. She received her postdoctoral training at NYU and Harvard Medical School. One of the focuses of the research in her laboratory is the understanding of the immune responses to implanted biomaterials.

Bibliographic Information

  • Book Title: Biomaterials in Regenerative Medicine and the Immune System

  • Editors: Laura Santambrogio

  • DOI: https://doi.org/10.1007/978-3-319-18045-8

  • Publisher: Springer Cham

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-18044-1Published: 15 September 2015

  • Softcover ISBN: 978-3-319-34802-5Published: 22 October 2016

  • eBook ISBN: 978-3-319-18045-8Published: 04 September 2015

  • Edition Number: 1

  • Number of Pages: IX, 280

  • Number of Illustrations: 23 b/w illustrations, 59 illustrations in colour

  • Topics: Biomaterials, Immunology, Biotechnology, Biomedical Engineering and Bioengineering

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access