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Whooping Cough Due to Bordetella pertussis and other Bordetella Subspecies

  • Book
  • Jul 2023

Overview

Authors:
  1. James D. Cherry

    1. David Geffen School of Medicine at UCLA, Los Angeles, USA

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  • The first comprehensive book on Bordetella pertussis to be published in 80 years

  • Examines misconceptions about pathogenesis, pertussis resurgence, and present approaches to this complex problem

  • Highlights historical aspects, clinical considerations, and modern diagnostic methods and treatments

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Keywords

About this book

Over the last century, interest in Bordetella pertussis and whooping cough has abounded at the same time as misunderstanding and misinformation about it proliferates and case numbers fluctuate. By the mid-twentieth century, B. pertussis was recognized and accepted as the cause of whooping cough, and newly developed vaccines were demonstrated to effectively prevent pertussis in children. Thousands of B. pertussis studies have since been carried out in mice, but over time further investigation has shown that the illness and its pathology in murine models is dissimilar from that of humans. Nevertheless, the findings in mice have led to the assumption by many Bordetella molecular microbiologists that their observations relate to human illness. The epidemiology B. pertussis infection is still not well understood by most epidemiologists and pertussis experts.

This book explores all aspects of B. pertussis and other Bordetella species that cause cough illnesses. It addresses the immunology, bacteriology, pathology, and serology, as well as the clinical epidemiology, public health considerations, diagnosis, treatment, and prevention of the clinical illnesses. The historical and evolutionary aspects of B. pertussis, B. holmesii and B. bronchiseptica infection and illness are also presented. The first complete book on whooping cough to be published in 80 years, this text is essential reading for medical students, researchers, and practitioners. 

Authors and Affiliations

  • David Geffen School of Medicine at UCLA, Los Angeles, USA

    James D. Cherry

About the author

James D. Cherry, M.D., M.Sc., is a Distinguished Professor of Pediatrics at the David Geffen School of Medicine, UCLA, and Mattel Children's Hospital UCLA, Division of Pediatric Infectious Diseases. He has spent more than 60 years in research, teaching, and clinical practice in the fields of infectious diseases and epidemiology. His laboratory experience has been in virology, mycoplasmology, and molecular microbiology relating to Bordetella species. Dr. Cherry's primary research has been related to vaccines and vaccine-preventable diseases, and much of his recent work relates to the epidemiology of Bordetella pertussis worldwide and its prevention by new vaccine strategies. At UCLA, he started the institution's first pediatric infectious diseases training program, and many of his trainees have gone on to become field leaders globally. Dr. Cherry is the author or co-author of over 550 publications (peer reviewed papers, commentaries, and book chapters). He is the lead editor of Feigin and Cherry's Textbook of Pediatric Infectious Diseases, now in its eighth edition (Elsevier, c. 2018). He is the recipient of numerous awards, including the Distinguished Physician Award from the Pediatric Infectious Diseases Society in 2003, the UCLA Medical Alumni Associations' Medical Science Award in 2005, and the IDSA's Alexander Fleming Lifetime Achievement Award in 2020. 

Bibliographic Information

  • Book Title: Whooping Cough Due to Bordetella pertussis and other Bordetella Subspecies

  • Authors: James D. Cherry

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2024

  • Softcover ISBN: 978-3-031-33774-1Due: 13 August 2024

  • eBook ISBN: 978-3-319-16754-1Due: 13 August 2023

  • Edition Number: 1

  • Number of Pages: X, 190

  • Number of Illustrations: 10 b/w illustrations, 10 illustrations in colour

  • Topics: Immunology, Vaccine, Infectious Diseases, Epidemiology

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