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Public Health | Pediatric Biomedical Informatics - Computer Applications in Pediatric Research

Pediatric Biomedical Informatics

Computer Applications in Pediatric Research

Hutton, John J. (Ed.)

2012, XX, 400 p.

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  • Examples are based upon the authors’ practical experiences in providing informatics support to numerous research programs in a large children’s hospital
  • Focuses on the linkage of informatics and information technology to research 
  • Introduces special challenges posed by support of clinical and basic research involving children and their families ​

Advances in the biomedical sciences, especially genomics, proteomics, and metabolomics, taken together with the expanding use of electronic health records, are radically changing the IT infrastructure and software applications needed to support the transfer of knowledge from bench to bedside. Pediatric Biomedical Informatics: Computer Applications in Pediatric Research describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital.  This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.

Dr. John Hutton is the Vice President and Director of Biomedical Informatics at Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. He is also Professor of Pediatrics and Associate Dean for Information Services at the University of Cincinnati College of Medicine.​

Content Level » Research

Keywords » biomedical informatics - biorepository - translational research

Related subjects » Bioinformatics - Pediatrics - Public Health

Table of contents 

Pediatric Electronic Health Records and Research.- Interfaces and Data Transmission Standards.- Data Storage and Access Management.- Institutional Cybersecurity in a Clinical Research Setting.- Protecting Privacy in the Child’s Electronic Health Record.- Research Patient Data Warehousing.- Biobanking in Pediatric Research.- EHR-linked Registries for Studies of Populations.- Natural Language Processing – The Basics.- Natural Language Processing: Applications in Pediatric Research.- Informatics and Decision Support.- Support of Perinatal and Neonatal Research.- Informatics Support of Outcomes Measures.- Patient Safety – Automated Detection and Reporting.- Network Analysis in Translational Research.- Orphan Diseases, Bioinformatics and Drug Discovery.- Transcriptional Networks – Control of Lung Maturation.- Defining Genetic Blueprints - Kidney and Craniofacial Development.- From SNP Genotyping to Improved Pediatric Healthcare.- Genetic Variation and Gene Discovery.

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