Skip to main content
Book cover

Detection of Non-Amplified Genomic DNA

  • Book
  • © 2012

Overview

  • The first book dedicated to amplification-free DNA analyses
  • Presents the most cutting-edge methods and probes to analyze DNA
  • Features DNA-sequencing techniques that offer advantages for timely results, enhanced sensitivity and reduced costs
  • Each chapter offers an introduction with the general principles of the method(s) under discussion
  • Self-contained chapters provide easy access and cater for the specific interests of individual readers

Part of the book series: Soft and Biological Matter (SOBIMA)

Buy print copy

Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Table of contents (11 chapters)

  1. DNA Analysis: Current Issues

  2. DNA analysis: current issues

  3. Advanced Materials for Ultrasensitive Analysis

  4. Advanced materials for ultrasensitive analysis

  5. Detection Strategies – Sensors

  6. Detection strategies - Sensors

  7. Detection Strategies – Sequencing

  8. Detection strategies - Sequencing

Keywords

About this book

This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.

Editors and Affiliations

  • , Department of Chemical Science, University of Catania, Catania, Italy

    Giuseppe Spoto

  • , Faculty of Science, University of Parma, Parma, Italy

    Roberto Corradini

About the editors

Prof. Giuseppe Spoto, University of Catania, Catania, Italy

Prof. Roberto Corradini, University of Parma, Parma, Italy

Bibliographic Information

Publish with us