Biomedical Devices and Their Applications

1. Front Matter

   Pages I-XIII

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2. Biomaterials in Drug Delivery

   • Anthony M. Lowman

   Pages 1-31

3. Drug Delivery Systems for Localized Treatment of Disease

   • James S. Marotta

   Pages 33-60

4. Application of Protein Electrophoresis Techniques

   • Alan H. Goldstein

   Pages 61-91

5. Xenoestrogens as Endocrine Disrupters

   • Nira Ben-Jonathan

   Pages 93-117

6. Medical Devices

   • G. J. Verkerke, H. F. Mahieu, A. A. Geertsema, I. F. Hermann, J. R. van Horn, J. M. Hummel et al.

   Pages 119-200

7. Back Matter

   Pages 201-201

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Biomedical devices that contact with blood or tissue represent a wide range of products. Depending on their potential harm to a body, medical devices are categorized according to the degree, so their safety can be assured. All biomaterials are by definition designed to contact with a body for a certain period of time. The nature of the body contact, as well as the duration a material contacts with the body may initiate unwanted biological In comparison with invasive devices Oike catheters and medical responses. implants contact directly with tissue or with the circulating blood) non­ invasive devices (like wound-dressings and contact lenses contact with the skin, the sclera, and the mucosa or with open wounds) have a lesser risk of hurting a patient. When blood contacts with a foreign material, plasma proteins become absorpted to the surface within a few seconds. The reactions that follow, the so-called intrinsic pathway lead to the formation of fibrin and activation of platelets and white blood cells, result in blood clot formation.

• Biomedical devices
• Medical Physics
• biomaterial
• drug
• drug delivery
• medical devices
• protein
• research

• Department of Chemical and Materials Engineering, University of Cincinnati, Cincinnati, USA

  Donglu Shi

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