Applications in Oncology and Cardiovascular Diseases
Kutikhin, Anton G., Yuzhalin, Arseniy E.
2013, XI, 185 p. 2 illus., 1 illus. in color.
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With numerous tables presenting the data systematically
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.