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New & Forthcoming Titles | Genomics of Pattern Recognition Receptors - Applications in Oncology and Cardiovascular Diseases

Genomics of Pattern Recognition Receptors

Applications in Oncology and Cardiovascular Diseases

Kutikhin, Anton G., Yuzhalin, Arseniy E.

2013, XI, 185 p. 2 illus., 1 illus. in color.

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  • Summarizes the field and indicates key directions
  • Explores and analyzes genomic variations
  • With numerous tables presenting the data systematically

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

Content Level » Research

Keywords » Cancer - Cardiovascular diseases - Immune response - NOD-like receptors - Pathogen-associated patterns - Toll-like receptors

Related subjects » Cancer Research - Cardiology & Angiology - Human Genetics - Immunology - Oncology & Hematology

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