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New & Forthcoming Titles | Intrinsically Disordered Protein Analysis - Volume 1, Methods and Experimental Tools

Intrinsically Disordered Protein Analysis

Volume 1, Methods and Experimental Tools

Series: Methods in Molecular Biology, Vol. 895

Uversky, Vladimir N., Dunker, A. Keith (Eds.)

2012, XIV, 511 p. 138 illus., 76 illus. in color.

A product of Humana Press
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  • Details experimental methods used both to identify IDP's and to analyse their structure.
  • Provides step-by-step detail essentiall for reproducible results
  • Contains key notes and implementation advice from the experts

Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis :Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 1 includes sections on assessing IDPs in the living cell,NMR based techniques, vibrational spectroscopy, and other spectroscopic techniques. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.


Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.

Content Level » Professional/practitioner

Keywords » IDPs - disorder - functional properties - globular proteins - physico-chemical - structural properties - unfolded proteins - unfoldomics

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