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  • Book
  • © 2014

Computational Methods for Three-Dimensional Microscopy Reconstruction

Birkhäuser
  • Features authors from three expert groups that have made pioneering contributions to this field
  • Provides interdisciplinary content that will appeal to mathematicians and biologists alike
  • Includes mathematically concise statements of image formation and structure recovery problems

Part of the book series: Applied and Numerical Harmonic Analysis (ANHA)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiii
  2. Introduction

    • Joachim Frank, Gabor T. Herman
    Pages 1-5
  3. Interchanging Geometry Conventions in 3DEM: Mathematical Context for the Development of Standards

    • C. O. S. Sorzano, R. Marabini, J. Vargas, J. OtĂłn, J. Cuenca-Alba, A. Quintana et al.
    Pages 7-42
  4. Fully Automated Particle Selection and Verification in Single-Particle Cryo-EM

    • Robert Langlois, Jordan T. Ash, Jesper Pallesen, Joachim Frank
    Pages 43-66
  5. Quantitative Analysis in Iterative Classification Schemes for Cryo-EM Application

    • Bingxin Shen, Bo Chen, Hstau Liao, Joachim Frank
    Pages 67-95
  6. High-resolution Cryo-EM Structure of the Trypanosoma brucei Ribosome: A Case Study

    • Amedee des Georges, Yaser Hashem, Sarah N. Buss, Fabrice Jossinet, Qin Zhang, Hstau Y. Liao et al.
    Pages 97-132
  7. Computational Methods for Electron Tomography of Influenza Virus

    • Younes Benkarroum, Paul Gottlieb, Al Katz, Stuart W. Rowland, Doris Bucher, Gabor T. Herman
    Pages 133-156
  8. Soft X-Ray Tomography Imaging for Biological Samples

    • J. OtĂłn, C. O. S. Sorzano, F. J. ChichĂłn, J. L. Carrascosa, J. M. Carazo, R. Marabini
    Pages 187-220
  9. Using Component Trees to Explore Biological Structures

    • Lucas M. Oliveira, T. Yung Kong, Gabor T. Herman
    Pages 221-255
  10. Back Matter

    Pages 257-264

About this book

Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ in detail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology.

Computational Methods for Three-Dimensional Microscopy Reconstruction will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in the area of 3D imaging and modeling.

Editors and Affiliations

  • Department of Computer Science, The Graduate Center City University of New York, New York, USA

    Gabor T. Herman

  • Department of Biology, Biochemistry and Molecular Biophysics, Columbia University, New York, USA

    Joachim Frank

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access