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Behavior Genetics of Psychopathology

  • Book
  • © 2014

Overview

Editors:
  1. Soo Hyun Rhee

    1. Department of Psychology and NeuroScience, University of Colorado, Boulder, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Angelica Ronald

    1. Department of Psychological Sciences, University of London, London, United Kingdom

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    You can also search for this editor in PubMed   Google Scholar

  • Chapters review literature on genetics of specific disorders
  • Examines topics that cut across diagnostic boundaries, such as gene-environment interaction and comorbidity
  • Reviews the state of genome-wide association studies and the potential for new sequencing studies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Behavior Genetics (AIBG, volume 2)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-viii
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  2. Attention Deficit Hyperactivity Disorder: Insight from Quantitative Genetic Research

    • Alexis C. Frazier-Wood, Anna S. Rommel, Jonna Kuntsi
    Pages 1-32

  3. Progress in Understanding the Causes of Autism Spectrum Disorders and Autistic Traits: Twin Studies from 1977 to the Present Day

    • Angelica Ronald, Rosa Hoekstra
    Pages 33-65

  4. Genetic Influences on Depression and Anxiety in Childhood and Adolescence

    • Frances Rice
    Pages 67-97

  5. Additional Evidence for Meaningful Etiological Distinctions Within the Broader Construct of Antisocial Behavior

    • S. Alexandra Burt
    Pages 99-119

  6. Sleep and Psychopathology: Quantitative and Molecular Genetic Research on Comorbidity

    • Nicola L. Barclay, Alice M. Gregory
    Pages 121-152

  7. Schizophrenia and Bipolar Disorder

    • Alastair G. Cardno, Edward Pepper
    Pages 153-183

  8. Genetics of Substance Use Disorders

    • Arpana Agrawal, Michael T. Lynskey
    Pages 185-230

  9. Behavioral Genetic Approaches to Understand the Etiology of Comorbidity

    • Erik G. Willcutt
    Pages 231-252

  10. Gene–Environment Interactions (G×E) in Behavioral Genetics

    • Laramie Duncan
    Pages 253-281

  11. Epigenetics of Psychopathology

    • Alicia K. Smith, Sasha E. Parets, Andrew W. Kim
    Pages 283-309

  12. Future Directions in Genetics of Psychiatric Disorders

    • Naomi R. Wray, Enda M. Byrne, Sven Stringer, Bryan J. Mowry
    Pages 311-337

  13. Back Matter

    Pages 339-344
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Keywords

About this book

As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and medical domains. The discoveries surrounding the human genome and the advancement in molecular genetic technologies have  led to studies becoming increasingly sophisticated and yielding  yet more conclusive and useful results. This is certainly the case in the area of child and adult psychopathology.

 

Behavior Genetics of Psychopathology summarizes the state of the field, examining

the role of genes and environment as they affect common neurodevelopmental and psychiatric conditions. Emphasizing key research areas (comorbidities, twin studies, the integration of methods), the book assesses the current literature, offers up-to-date findings, sorts through lingering controversies, and identifies a clear future agenda for the field. Expertly-written chapters focus on issues of both general salience that shape behavior genetics of psychopathology, to specific disorders of major clinical importance, among them:

 

  • ADHD: the view from quantitative genetic research.
  • Autism spectrum disorders and their complex heterogeneity
  • Genetic influences on anxiety and depression in childhood and adolescence.
  • Evidence for etiologically-defined subgroups within the construct of antisocial behavior.
  • Sleep and psychopathology: the reasons for their co-occurrence.
  • Behavioral genetic approaches to the etiology of comorbidity.
  • Epigenetics of psychopathology.

 

This combination of timeliness and depth of coverage make Behavior Genetics of Psychopathology a frontline resource for behavior geneticists, psychologists, psychiatrists, and neuroscientists, and is perfectly suited to graduate students looking to join these fields.

Editors and Affiliations

  • Department of Psychology and NeuroScience, University of Colorado, Boulder, USA

    Soo Hyun Rhee

  • Department of Psychological Sciences, University of London, London, United Kingdom

    Angelica Ronald

About the editors

Soo Hyun Rhee, PhD is as associate professor in the Department of Psychology and Neuroscience and faculty fellow at the Institute for Behavioral Genetics at the University of Colorado-Boulder. She is currently working on a study examining a developmental model of conduct disorder in a longitudinal, genetically informative sample focusing on negative emotionality, daring, and lack of prosociality as early precursors of conduct problems. Angelina Ronald, PhD is a lecturer at the Centre for Brain and Cognitive Development in the Department of Psychological Sciences at Birkbeck, University of London. She is known for her behavior genetics research on developmental psychopathology. Dr. Ronald is a collaborator on several large twin studies and is also a scientific affiliate of the British Autism Study of Infant Siblings (BASIS).

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