Overview
- State of the art in tumor modelling
- It stresses the role of biomedical scientists working in modelling
- Original interdisciplinary insight into the biomedical applications
- Includes supplementary material: sn.pub/extras
Part of the book series: SEMA SIMAI Springer Series (SEMA SIMAI)
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Table of contents (20 chapters)
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Front Matter
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Towards a Comprehensive Theory of Cancer Growth
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Front Matter
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Cancer Related Signalling Pathways
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Front Matter
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Basic Mechanisms of Tumor Progression
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Front Matter
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Tumor-Immune System Interplay and Immunotherapy
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Front Matter
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Computational Method for Improving Chemotherapy
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Front Matter
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Keywords
About this book
The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the global behavior of the biological process under consideration. It becomes increasingly evident that the tools to construct such complex models include, not only bioinformatics and modern applied statistics, as is unanimously agreed, but also other interdisciplinary fields of science, notably, Mathematical Oncology, Systems Biology and Theoretical Biophysics.
Editors and Affiliations
About the editors
Alberto d’Onofrio is principal investigator in Systems Biomedicine at the European Institute of Oncology. His research interests focus on the application of mathematical and theoretical physics methodologies to study tumor biology, and the spread of infectious diseases. Webpage: http://www.ifom-ieo-campus.it/research/donofrio.php
Paola Cerrai is researcher at the Department of Mathematics of Pisa University, where she lectures in Mathematics and Statistics at the faculty of Biology. Her research interests focus on Mathematical Biology and Medicine. In particular: population dynamics, motion of bacteria and, more recently, growth of tumours and their interactions with the Immune System. She is also interested in the process (and in the related difficulties) of learning probability and statistics. She is intensely active in promoting the interdisciplinary cultural dialogue by organizing conferences and seminars.
Alberto Gandolfi works at Istituto di analisi dei Sistemi e di Informatica.
Bibliographic Information
Book Title: New Challenges for Cancer Systems Biomedicine
Editors: Alberto d’Onofrio, Paola Cerrai, Alberto Gandolfi
Series Title: SEMA SIMAI Springer Series
DOI: https://doi.org/10.1007/978-88-470-2571-4
Publisher: Springer Milano
eBook Packages: Mathematics and Statistics, Mathematics and Statistics (R0)
Copyright Information: Springer-Verlag Italia Srl. 2012
Hardcover ISBN: 978-88-470-2570-7Published: 17 October 2012
Softcover ISBN: 978-88-470-5617-6Published: 09 November 2014
eBook ISBN: 978-88-470-2571-4Published: 25 January 2013
Series ISSN: 2199-3041
Series E-ISSN: 2199-305X
Edition Number: 1
Number of Pages: XV, 399
Topics: Physiological, Cellular and Medical Topics, Cancer Research, Biological and Medical Physics, Biophysics, Partial Differential Equations, Immunology