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Nitrite and Nitrate in Human Health and Disease

  • Book
  • © 2011

Overview

Editors:
  1. Nathan S. Bryan

    1. Health Science Center, Houston, Inst. Molecular Medicine, University of Texas, Houston, USA

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  2. Joseph Loscalzo

    1. Brigham & Women's Hospital, Harvard Medical School, Boston, USA

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  • Introduces nitric oxide and provides a biochemical analysis of its roles in human physiology
  • Offers evidence showing how NO-rich foods are linked to disease prevention and healthy modulation of human physiological functions
  • Reviews research on therapeutic applications of NO and NO metabolites

Part of the book series: Nutrition and Health (NH)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xxii
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  2. Basic Biochemistry, Metabolism, and Physiology

    1. Front Matter

      Pages 1-1
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  3. BASIC BIOCHEMISTRY, METABOLISM AND PHYSIOLOGY

    1. Introduction

      • Nathan S. Bryan, Joseph Loscalzo
      Pages 3-7

    2. From Atmospheric Nitrogen to Bioactive Nitrogen Oxides

      • Mark Gilchrist, Nigel Benjamin
      Pages 9-19

    3. The Nitrate–Nitrite–Nitric Oxide Pathway in Mammals

      • Jon O. Lundberg, Eddie Weitzberg, Sruti Shiva, Mark T. Gladwin
      Pages 21-48

    4. Sources of Exposure to Nitrogen Oxides

      • Andrew L. Milkowski
      Pages 49-65

  4. Food and Environmental Exposures to Nitrite and Nitrate

    1. Front Matter

      Pages 67-67
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  5. FOOD AND ENVIRONMENTAL EXPOSURES TO NITRITE AND NITRATE

    1. History of Nitrite and Nitrate in Food

      • Jimmy T. Keeton
      Pages 69-84

    2. Nutritional Epidemiology of Nitrogen Oxides: What do the Numbers Mean?

      • Martin Lajous, Walter Willett
      Pages 85-96

    3. Nutritional Impact on the Nitric Oxide Pathway

      • Wing Tak Wong, John P. Cooke
      Pages 97-122

    4. Dietary Flavonoids as Modulators of NO Bioavailability in Acute and Chronic Cardiovascular Diseases

      • Matthias Totzeck, Malte Kelm, Tienush Rassaf
      Pages 123-137

    5. Nitrite and Nitrate in Human Breast Milk: Implications for Development

      • Pamela D. Berens, Nathan S. Bryan
      Pages 139-153

    6. Regulation of Dietary Nitrate and Nitrite: Balancing Essential Physiological Roles with Potential Health Risks

      • Norman G. Hord
      Pages 155-166

  6. Nitrite and Nitrate in Therapeutics and Disease

    1. Front Matter

      Pages 167-167
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  7. NITRITE AND NITRATE IN THERAPEUTICS AND DISEASE

    1. Nitric Oxide Signaling in Health and Disease

      • Nathan S. Bryan, Jack R. Lancaster Jr.
      Pages 169-186

    2. Inhaled Nitric Oxide

      • Kenneth D. Bloch, Andrea U. Steinbicker, Lisa K. Lohmeyer, Rajeev Malhotra
      Pages 187-205

    3. Pharmacology of Nitrovasodilators

      • Nathaniel A. Page, Ho-Leung Fung
      Pages 207-224

    4. Nitrite and Nitrate in Ischemia-Reperfusion Injury

      • Madhav Lavu, Susheel Gundewar, David J. Lefer
      Pages 225-246

    5. The Nitrate–Nitrite–Nitric Oxide Pathway in Traditional Herbal Medicine for Heart Disease

      • Yong-Jian Geng
      Pages 247-261

    6. Nitrite and Nitrate in Cancer

      • David M. Klurfeld
      Pages 263-278
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Keywords

About this book

Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body.  Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate.  The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing.  This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government.  Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.

Editors and Affiliations

  • Health Science Center, Houston, Inst. Molecular Medicine, University of Texas, Houston, USA

    Nathan S. Bryan

  • Brigham & Women's Hospital, Harvard Medical School, Boston, USA

    Joseph Loscalzo

Bibliographic Information

  • Book Title: Nitrite and Nitrate in Human Health and Disease

  • Editors: Nathan S. Bryan, Joseph Loscalzo

  • Series Title: Nutrition and Health

  • DOI: https://doi.org/10.1007/978-1-60761-616-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2011

  • Softcover ISBN: 978-1-61779-733-0Published: 28 May 2013

  • eBook ISBN: 978-1-60761-616-0Published: 15 April 2011

  • Series ISSN: 2628-197X

  • Series E-ISSN: 2628-1961

  • Edition Number: 1

  • Number of Pages: XXII, 306

  • Topics: Clinical Nutrition, Nutrition, Public Health, Food Science

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