Overview
- Includes cutting-edge methods and protocols with a focus on TNF Superfamily members in health and disease
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1155)
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Table of contents (18 protocols)
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Front Matter
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Back Matter
Keywords
About this book
Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.
Editors and Affiliations
Bibliographic Information
Book Title: The TNF Superfamily
Book Subtitle: Methods and Protocols
Editors: Jagadeesh Bayry
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-0669-7
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2014
Hardcover ISBN: 978-1-4939-0668-0Published: 01 May 2014
Softcover ISBN: 978-1-4939-5392-9Published: 23 August 2016
eBook ISBN: 978-1-4939-0669-7Published: 30 April 2014
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 226
Number of Illustrations: 28 b/w illustrations, 15 illustrations in colour
Topics: Protein Science