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  • © 2012

Functional Coherence of Molecular Networks in Bioinformatics

  • Intersects broad sub-disciplines within biology, statistics and computer sciences
  • Motivates a number of open problems, which provide excellent avenues for continuing efforts in the area
  • Focuses on the computational challenges associated with systems-level modeling of biological function

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-x
  2. Introduction to Network Biology

    • Mehmet Koyutürk, Shankar Subramaniam, Ananth Grama
    Pages 1-13
  3. Topological Characteristics of Molecular Networks

    • Tijana Milenković, Nataša Pržulj
    Pages 15-48
  4. Function Annotation in Gene Networks

    • Petko Bogdanov, Kathy Macropol, Ambuj K. Singh
    Pages 49-67
  5. Proteome Network Emulating Models

    • Phuong Dao, Fereydoun Hormozdiari, Iman Hajirasouliha, Martin Ester, S. Cenk Sahinalp
    Pages 69-95
  6. Biological Network Alignment

    • Shahin Mohammadi, Ananth Grama
    Pages 97-136
  7. Pattern Mining Across Many Massive Biological Networks

    • Wenyuan Li, Haiyan Hu, Yu Huang, Haifeng Li, Michael R. Mehan, Juan Nunez-Iglesias et al.
    Pages 137-170
  8. Molecular Networks and Complex Diseases

    • Mehmet Koyutürk, Sinan Erten, Salim A. Chowdhury, Rod K. Nibbe, Mark R. Chance
    Pages 171-199
  9. Back Matter

    Pages 221-228

About this book

Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

Editors and Affiliations

  • Department of Electrical Engineering & C, Case Western Reserve University, Cleveland, USA

    Mehmet Koyutürk

  • Department of Bioengineering, University of California, San Diego, La Jolla, USA

    Shankar Subramaniam

  • Department of Computer Science, Purdue University, West Lafayette, USA

    Ananth Grama

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access