Plas, E., Pflüger, H., Maier, U., Hübner, W.A. (Eds.)
Softcover reprint of the original 1st ed. 2004, XII, 173 p. 61 illus., partly in color.
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Aging is associated with morphologic and functional alterations of organ systems including the genitourinary tract. Aging of the bladder leads to urgency, frequency, dysuria, recurrent urinary tract infections and incontinence both in the aging men and women. These symptoms occur frequently, are very distressing and influence daily life of the aging person. Besides patients symptoms, medications and incontinence devices are a tremendous financial burden on health care systems. Understanding the morphologic and functional processes of the aging bladder may decrease symptoms, costs and develop new, preventive strategies for the treatment of the aging bladder.
This book reviews present knowledge of morphologic and functional alterations of the aging bladder both in men and women adding new insights in order to optimize therapeutic options for the treatment of aging bladder in daily practice and improve patients quality of life.
Anatomy and pathophysiology of the aging bladder.- Epidemiology and symptomatology of the aging bladder.- Morphology and ultrastructure of the aging bladder.- Muscarinic receptors and the aging bladder.- Changes in the receptor profile of the lower urinary tract in the aging male.- Calcium met abolism and detrusor failure in the aging bladder.- The significance of the urine-blood-barrier for urge generation and possible changes in the aging bladder.- The impact of changes in fluid regulation hormones during aging.- Impact of central nervous system alt erations to bladder dysfunction in elderly people.- Urodynamic findings in aging people.- Pathophysiology orientated therapy of the aging bladder.- Hormonal replacement therapy for the aging bladder.- Physiology and pathophysiolo gy of bowel motility during aging and its therapeutic implications.