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Today's investigator, overwhelmed by the information avalanche, may find it difficult to analyze emerging advances in technology. In Renal Disease: Techniques and Protocols, leading experts distill their experience into user-friendly methods for studying fluid-electrolyte homeostasis and kidney function in health and disease. Described in step-by-step detail, the techniques move from the molecular level to the whole organism, and from simple models to integrative physiology. Here the researcher will find established disease models, methods for optimizing renal disease research, as well as much help in choosing imaging techniques for studies of the kidney's structure and function in health, disease, and during embryonic development. Subjects covered include molecular diagnostics, strategies for studying the molecular mechanisms of kidney disease, technical means to assess the functional correlates of disease, and the planning of clinical trials. In addition to detailed instructions, each cutting-edge method includes troubleshooting advice, lists of reagents, and tips on avoiding pitfalls.
State-of-the-art and highly practical, Renal Disease: Techniques and Protocols is not only a vade mecum for the many techniques employed to study the kidney in health and disease today, but also a user-friendly guide for the uninitiated, and a thoughtful consult for the experienced researcher.