Logo - springer
Slogan - springer

Medicine - Surgery | Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach

Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach

De Ponte, Francesco Saverio (Ed.)

2012, XIII, 181 p. 98 illus., 76 illus. in color.

Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-88-470-2083-2

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase

learn more about Springer eBooks

add to marked items


Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-88-470-2082-5

free shipping for individuals worldwide

online orders shipping within 2-3 days.

add to marked items

  • First multidisciplinary text on the subject, by worldwide experts
  • Update of the latest advances, technical details, and expert advice regarding this subject
  • Presents multiple designs, explanatory figures on physiopathogenesis, and clinical imaging
  • Clinical case discussions and practical advice for incorporation into common practice
Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated with oral BF for osteoporosis has been also highlighted, though rarely. On the basis of the large use of BF, of their pharmacokinetics, of the systemic and local risk factors, physicians prescribing them and dental surgeons should be well informed on the various aspects of the problem. Aim of this volume is to offer an update on the current status of prevention, and on the current conservative and surgical treatments. The multidisciplinary approach will be very much appreciated by GP’s, the different specialists using bisphosphonates and by dental surgeons.

Content Level » Professional/practitioner

Keywords » bisphosphonates - osteonecrosis - pharmacology - surgery - tumor

Related subjects » Dentistry - Internal Medicine - Medicine - Pharmacology & Toxicology - Radiology - Surgery

Table of contents 

Preface-1. Introduction - 2. Pharmacology: Mechanism of Action of Bisphosphonates- 3. Use of Bisphosphonates in Oncology, Hematology  and Osteoporosis - 4. Biomorphology in BIONJ: Anatomy and History - 5. Ethiopathogenesis and clinic of BIONJ - 6. Instrumental Diagnosis.- 7. Microbiological Aspects - 8. Prevention and role of Dentist - 9. Conservative Treatment: Oxygen, Ozone and Laser - 10. Minimally Invasive Surgical Treatment - 11. Major Surgery in BIONJ - 12. The future of BIONJ 

Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Oral and Maxillofacial Surgery.