Neurovascular Events After Subarachnoid Hemorrhage

1. Front Matter

   Pages i-xiv

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2. Vasospasm: My First 25 Years—What Worked? What Didn’t? What Next?

   • R. Loch Macdonald

   Pages 1-10

3. Aneurysm Formation

   1. Front Matter

      Pages 11-11

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   2. Molecular Basis for Intracranial Aneurysm Formation

      • Miyuki Fukuda, Tomohiro Aoki

      Pages 13-15

   3. Aneurysm Wall Thickness Measurements of Experimental Aneurysms: In Vivo High-Field MR Imaging Versus Direct Microscopy

      • Camillo Sherif, Günther Kleinpeter, Michel Loyoddin, Georg Mach, Roberto Plasenzotti, Thomas Haider et al.

      Pages 17-20

4. Early Brain Injury and Neuroprotection

   1. Front Matter

      Pages 21-21

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   2. Early Events After Aneurysmal Subarachnoid Hemorrhage

      • Fatima A. Sehba, Victor Friedrich

      Pages 23-28

   3. Mouse Genetic Background Is Associated with Variation in Secondary Complications After Subarachnoid Hemorrhage

      • Josephine A. D’Abbondanza, Elliot Lass, Jinglu Ai, R. Loch Macdonald

      Pages 29-33

   4. The Value of Perfusion Computed Tomography (PCT) Imaging After Aneurysmal Subarachnoid Hemorrhage: A Review of the Current Data

      • Kerim Beseoglu, Nima Etminan, Daniel Hänggi

      Pages 35-38

   5. Neurovascular Events After Subarachnoid Hemorrhage: Focusing on Subcellular Organelles

      • Sheng Chen, Haijian Wu, Jiping Tang, Jianmin Zhang, John H. Zhang

      Pages 39-46

   6. Effects of Diltiazem on Sympathetic Activity in Patients with Aneurysmal Subarachnoid Hemorrhage

      • Takeshi Ogura, Ririko Takeda, Hidetoshi Ooigawa, Hiroyuki Nakajima, Hiroki Kurita

      Pages 47-50

   7. Haemoglobin Scavenging After Subarachnoid Haemorrhage

      • A. Durnford, J. Dunbar, J. Galea, D. Bulters, J. A. R. Nicoll, D. Boche et al.

      Pages 51-54

   8. Mild Exercise Reduces Cerebral Vasospasm After Aneurysm Subarachnoid Hemorrhage: A Retrospective Clinical Study and Correlation with Laboratory Investigation

      • Margaret A. Riordan, Michele Kyle, Christina Dedeo, Mark R. Villwock, Matthew Bauer, Mary Lou Vallano et al.

      Pages 55-61

   9. Time-Dependent Changes in Cerebrospinal Fluid Metal Ions Following Aneurysm Subarachnoid Hemorrhage and Their Association with Cerebral Vasospasm

      • Amit Singla, Mark R. Villwock, Margaret A. Riordan, David J. Padalino, Eric M. Deshaies

      Pages 63-68

   10. Effects of Tenascin-C on Early Brain Injury After Subarachnoid Hemorrhage in Rats

       • Masato Shiba, Masashi Fujimoto, Fumio Kawakita, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Kenji Kanamaru et al.

       Pages 69-73

   11. The Role of Erythropoietin in Aneurysmal Subarachnoid Haemorrhage: From Bench to Bedside

       • Giovanni Grasso, Michele Buemi, Filippo Giambartino

       Pages 75-80

   12. Valproic Acid Treatment After Experimental Subarachnoid Hemorrhage

       • Michael K. Tso, Elliot Lass, Jinglu Ai, R. Loch Macdonald

       Pages 81-85

5. Macro- and Microcirculatory Disturbance

   1. Front Matter

      Pages 87-87

      PDF

   2. SAH-Induced MMP Activation and K _V Current Suppression is Mediated Via Both ROS-Dependent and ROS-Independent Mechanisms

      • Masayo Koide, George C. Wellman

      Pages 89-94

   3. Mechanisms Underlying Increased Vascular Smooth Muscle Contractility in the Rabbit Basilar Artery Following Subarachnoid Hemorrhage

      • Yuichiro Kikkawa, Katsuharu Kameda, Satoshi Matsuo, Ryota Kurogi, Akira Nakamizo, Masahiro Mizoguchi et al.

      Pages 95-98

This book contains articles presented at the 12th International Conference on Cerebral Vasospasm, held in Lucerne, Switzerland, in July 2013. The included papers represent a balanced cross-section of the enormous progress achieved in basic and clinical research on aneurysmal subarachnoid hemorrhage and its sequelae, including early neurovascular events and delayed cerebral vasospasm. The section on basic research covers a broad range of aspects, with a special focus on animal models for the study of acute events after experimental subarachnoid hemorrhage. The section on clinical topics encompasses imaging and endovascular management, surgical innovations and techniques, management and monitoring in neurocritical care, the status of clinical trials, and factors involved in aneurysm formation. This edition is of interest not only for basic researchers but also for clinicians who wish to apply state-of-the-art knowledge to the research and management of this devastating condition.

• Aneurysm Formation
• Blood-Brain-Barrier Disruption
• Brain injury
• Endovascular

• Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland

  Javier Fandino, Serge Marbacher, Ali-Reza Fathi, Carl Muroi

• Department of Neurosurgery Neurointensive Care Unit, University Hospital Zurich, Zurich, Switzerland

  Emanuela Keller

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