Artificial Organs

1. Front Matter

   Pages i-x

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2. Management of Multiorgan Failure After Artificial Organ Implantation

   • Michael Devile, Parind Patel, Carlos Mh Gómez

   Pages 1-19

3. Artificial Circulatory Support

   • John Mulholland

   Pages 21-37

4. The Artificial Kidney

   • Christopher Kirwan, Andrew Frankel

   Pages 39-55

5. Liver Substitution

   • Sambit Sen, Roger Williams

   Pages 57-76

6. Glucose Sensors and Insulin Pumps: Prospects for an Artificial Pancreas

   • Martin Press

   Pages 77-91

7. From Basic Wound Healing to Modern Skin Engineering

   • L. C. Andersson, H.C. Nettelblad, G. Kratz

   Pages 93-105

8. Artificial Sphincters

   • Austin Obichere, Ibnauf Suliman

   Pages 107-132

9. Cochlear Implant

   • George Fayad, Behrad Elmiyeh

   Pages 133-136

10. Stem Cells and Organ Replacement

    • Nataša Levičar, Ioannis Dimarakis, Catherine Flores, Evangelia I Prodromidi, Myrtle Y Gordon, Nagy A Habib

    Pages 137-163

11. Composite Tissue Transplantation: A Stage Between Surgical Reconstruction and Cloning

    • Earl R. Owen, Nadey S. Hakim

    Pages 165-177

12. Back Matter

    Pages 179-183

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Artificial organs have come a long way since the first dialysis machine, the rotating artificial kidney, was invented in 1944 by Willem Johan Kolff, who is known as the ‘‘father of artificial organs’’. At that time he met stiff resistance from his hospital superiors but his persistence paid off and a million saved lives have been attributed to his first invention. He was indeed the first to mix medicine and engineering. An artificial organ is any machine, device, or other material that is used to replace the functions of a faulty or missing organ or other parts of the human body. Some body parts are more of a challenge than others. The heart has one purpose and it is to pump blood; however, the liver has biochemical and physiological functions which are difficult to simulate. The implantation of an artificial organ is critical because of the patient life dependency on the artificial organ itself. The treatment of choice is organ transplantation, however, transplant candidates face a long waiting time and many die while on the waiting list. In addition there are patients who are excluded from transplantation because of age or presence of other diseases. This book p- sents an overview of the current state of knowledge of artificial organs including the liver, pancreas, kidney, heart, cochlea, skin, stem cells, composite tissue allograft, and sphincters.

• Artificial Organs
• Implantat
• cells
• multiorgan failure
• organ replacement
• tissue

Policies and ethics