Editors:
Groundbreaking, multidisciplinary title developed by a group of renowned experts
Comprehensive overview of brain death and the selection of suitable brain-dead organ donors
State-of-the-art discussion and guidlines of how a potential organ donor should be managed to ensure maximum use of the organs and cells
Includes supplementary material: sn.pub/extras
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Table of contents (28 chapters)
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Front Matter
About this book
Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death.  That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models.  This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic ‘storm’, that takes place during and following the induction of brain death, and how they impact metabolism.  The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and  those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists. Â
Editors and Affiliations
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Tampa VA Medical Center, Surgery, University of South Florida, Tampa, USA
Dimitri Novitzky
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Thomas E. Starzl Transplantation Institu, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, USA
David K C Cooper
Bibliographic Information
Book Title: The Brain-Dead Organ Donor
Book Subtitle: Pathophysiology and Management
Editors: Dimitri Novitzky, David K C Cooper
DOI: https://doi.org/10.1007/978-1-4614-4304-9
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-4614-4303-2Published: 28 October 2012
Softcover ISBN: 978-1-4939-4186-5Published: 23 August 2016
eBook ISBN: 978-1-4614-4304-9Published: 26 October 2012
Edition Number: 1
Number of Pages: XVI, 368
Topics: Surgery, Intensive / Critical Care Medicine, Neurosurgery, Neurology, Endocrinology, Pathology