Logo - springer
Slogan - springer

Medicine - Rheumatology | Behçet's Disease - From Genetics to Therapies

Behçet's Disease

From Genetics to Therapies

Ishigatsubo, Yoshiaki (Ed.)

2015, IX, 176 p. 38 illus., 31 illus. in color.

Available Formats:

Springer eBooks may be purchased by end-customers only and are sold without copy protection (DRM free). Instead, all eBooks include personalized watermarks. This means you can read the Springer eBooks across numerous devices such as Laptops, eReaders, and tablets.

You can pay for Springer eBooks with Visa, Mastercard, American Express or Paypal.

After the purchase you can directly download the eBook file or read it online in our Springer eBook Reader. Furthermore your eBook will be stored in your MySpringer account. So you can always re-download your eBooks.


(net) price for USA

ISBN 978-4-431-54487-6

digitally watermarked, no DRM

Included Format: PDF and EPUB

download immediately after purchase

learn more about Springer eBooks

add to marked items


Hardcover version

You can pay for Springer Books with Visa, Mastercard, American Express or Paypal.

Standard shipping is free of charge for individual customers.


(net) price for USA

ISBN 978-4-431-54486-9

free shipping for individuals worldwide

usually dispatched within 3 to 5 business days

add to marked items

  • Provides comprehensive information on Behçet's disease
  • Covers the latest findings, including genetic studies and treatment
  • An essential resource for both basic researchers and clinical physicians​

This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease.
Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease:  From Genetics to Therapies  provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.​

Content Level » Professional/practitioner

Keywords » Autoimmune - Uveitis - anti-TNF-alpha antibodies

Related subjects » Dermatology - Internal Medicine - Ophthalmology - Rheumatology

Table of contents 

1. Overview.- 2. The Immunopathology of Behcet’s Disease.- 3. Genetics.- 4. Ocular Involvement.- 5. Vascular Involvement of Behçet’s Disease.- 6. Neurological Involvement.- 7. Gastrointestinal Involvement.- 8. Mucocutaneous Manifestations.- 9. Perspective​.

Popular Content within this publication 



Read this Book on Springerlink

Services for this book

New Book Alert

Get alerted on new Springer publications in the subject area of Rheumatology.