Overview
Provides comprehensive information on Behçet's disease
Covers the latest findings, including genetic studies and treatment
An essential resource for both basic researchers and clinical physicians?
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Table of contents (9 chapters)
Keywords
About this book
This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease.
Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
Editors and Affiliations
Bibliographic Information
Book Title: Behçet's Disease
Book Subtitle: From Genetics to Therapies
Editors: Yoshiaki Ishigatsubo
DOI: https://doi.org/10.1007/978-4-431-54487-6
Publisher: Springer Tokyo
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Japan 2015
Hardcover ISBN: 978-4-431-54486-9Published: 15 December 2014
Softcover ISBN: 978-4-431-56170-5Published: 23 August 2016
eBook ISBN: 978-4-431-54487-6Published: 03 December 2014
Edition Number: 1
Number of Pages: IX, 176
Number of Illustrations: 7 b/w illustrations, 31 illustrations in colour
Topics: Rheumatology, Allergology, Dermatology, Ophthalmology, Gastroenterology