Intensity-Modulated Radiation Therapy

1. Front Matter

   Pages i-viii

   PDF

2. Foundations and Techniques

   1. Front Matter

      Pages 1-1

      PDF

   2. History of IMRT

      • Michael D. Mills, Shiao Y. Woo

      Pages 3-14

   3. Principles of IMRT

      • Laurence E. Court, Peter Balter, Radhe Mohan

      Pages 15-42

   4. Radiobiology for IMRT

      • Yuta Shibamoto, Chikao Sugie, Hiroyuki Ogino, Natsuo Tomita

      Pages 43-57

   5. Treatment Planning of IMRT for Head and Neck Malignancies

      • Toru Shibata

      Pages 59-84

   6. IGRT for IMRT

      • Hidenobu Tachibana, Tetsuo Akimoto

      Pages 85-112

   7. Adaptive Radiation Therapy in Intensity-Modulated Radiation Therapy for Head and Neck Cancer

      • Yasumasa Nishimura

      Pages 113-127

3. Clinical Application

   1. Front Matter

      Pages 129-129

      PDF

   2. Brain Tumor: How Should We Manage Glioblastoma in the Era of IMRT?

      • Toshihiko Iuchi, Kazuo Hatano

      Pages 131-151

   3. Nasopharyngeal Cancer

      • Moses M. Tam, Nadeem Riaz, Nancy Y. Lee

      Pages 153-169

   4. Oropharyngeal Cancer

      • Takeshi Kodaira, Arisa Shimizu, Keiichi Takehana

      Pages 171-192

   5. Postoperative Intensity-Modulated Radiation Therapy for Head and Neck Cancers: A Case-Based Review

      • G. Brandon Gunn, Adam S. Garden

      Pages 193-213

   6. Sequelae of Therapy of Head and Neck Cancer: Their Prevention and Therapy

      • Amrut S. Kadam, Avraham Eisbruch

      Pages 215-248

   7. Non-small Cell Lung Cancer

      • Quynh-Nhu Nguyen, Ritsuko Komaki, Daniel R. Gomez, Zhongxing Liao

      Pages 249-260

   8. Mesothelioma

      • William W. Chance, Neal Rebueno, Daniel R. Gomez

      Pages 261-273

   9. Breast Cancer

      • Gregory M. Chronowski

      Pages 275-288

   10. Clinical Application of IMRT for Cervical Esophageal Cancer

       • Satoshi Itasaka

       Pages 289-299

   11. Thoracic Esophageal Cancer

       • Steven H. Lin

       Pages 301-314

   12. Pancreatic Cancer

       • Keiko Shibuya, Takehiro Shiinoki, Akira Nakamura

       Pages 315-336

Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist.

• high-dose radiation
• radiation oncology
• radiobiology
• treatment planning
• Radiaton Oncology

“The book is well written and illustrated and each chapter is extensively referenced. The strength of the book is the breadth of its content which lends it to readers looking to have an overview of the subject and will therefore be suited to radiation oncology trainees, therapeutic radiographers and trainee physicists. … The addition of this book to the current stock in the libraries of radiation oncology facilities where training is undertaken should be considered.” (Dr. John Logue, RAD Magazine, December, 2015)

“The book covers foundations and techniques for IMRT. It has the added benefit of including emerging technologies such as adaptive radiation therapy (ART) and the use of molecular imaging techniques for preferential targeting of high tumor burden regions. … this would be a nice addition to the library of a medical physics or radiation oncology resident.” (Carri K. Glide-Hurst, Doody’s Book Reviews, October, 2015)

• Department of Radiation Oncology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan

  Yasumasa Nishimura

• Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA

  Ritsuko Komaki

Policies and ethics