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Acute and Long-Term Side-Effects of Radiotherapy

Biological Basis and Clinical Relevance

  • Conference proceedings
  • © 1993

Overview

Editors:
  1. Wolfgang Hinkelbein

    1. Abteilung Strahlentherapie, Radiologische Universitätsklinik, Freiburg, Germany

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  2. Gregor Bruggmoser

    1. Abteilung Strahlentherapie, Radiologische Universitätsklinik, Freiburg, Germany

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  3. Hermann Frommhold

    1. Abteilung Strahlentherapie, Radiologische Universitätsklinik, Freiburg, Germany

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  4. Michael Wannenmacher

    1. Abteilung Radiologie, Radiologische Universitätsklinik, Heidelberg, Germany

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 130)

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Table of contents (24 papers)

  1. Front Matter

    Pages I-XII
    Download chapter PDF

  2. Basic Principles

    1. Microvasculature and Radiation Damage

      • J. W. Hopewell, W. Calvo, R. Jaenke, H. S. Reinhold, M. E. C. Robbins, E. M. Whitehouse
      Pages 1-16

    2. The Time Factor for Late Reactions in Radiotherapy: Repopulation or Intracellular Repair?

      • J. H. Hendry, Y.-M. Jen
      Pages 17-26

    3. The Response of Tissues to Very Low Doses per Fraction: A Reflection of Induced Repair?

      • M. C. Joiner, B. Marples, H. Johns
      Pages 27-40

    4. Clinically Important Factors Modifying the Response of Tumors and Normal Tissue to Radiation Therapy

      • K.-H. Hübener, M. Baumann, A. Krüll, R. Schwarz
      Pages 41-47

  3. Radiation Response of Mucosa and Skin, Muscle and Bladder

    1. Dose-Response Relationships for Late Effects on Skin and Mucosa

      • I. Turesson
      Pages 49-57

    2. Early and Late Normal Tissue Injury after Postmastectomy Radiotherapy

      • S. M. Bentzen, M. Overgaard
      Pages 59-78

    3. Muscle Injury in Experimental Intraoperative Irradiation

      • E. L. Gillette, B. E. Powers, S. McChesney Gillette, T. B. Borak
      Pages 79-87

    4. An Experimental In Vivo Model in Mice to Evaluate the Change in Reservoir Function of the Urinary Bladder due to Irradiation Alone or Combined with Chemotherapy

      • F. Lundbeck
      Pages 89-102

    5. Combined Chemo-Radiotherapy with Carboplatin, 5-Fluorouracil and Folinic Acid for Cancer of the Urinary Bladder: Acute and Late Side Effects

      • T. Wiegel, J. Lorenzen, W.-P. Brockmann, B. Lopez, R. Schwarz, K.-H. Hübener
      Pages 103-107

  4. Radiation Effects on Lung and Heart

    1. Radiopathology of the Lung: Experimental and Clinical Observations

      • M. Molls, Th. Herrmann, F. Steinberg, H. J. Feldmann
      Pages 109-121

    2. Diagnosis of Radiation-Pneumonitis

      • G. Sigmund, J. Slanina, W. Hinkelbein
      Pages 123-131

    3. Lung Effects after Total Body Irradiation of Mice and Bone Marrow Transplant Patients: Comparison of Experimental and Preliminary Clinical Data

      • F. Steinberg, K. Quabeck, B. Rehn, R. Kraus, M. Mohnke, U. Costabel et al.
      Pages 133-143

    4. Experimental Studies on the Pathogenesis of Damage in the Heart

      • S. Schultz-Hector
      Pages 145-156

    5. Myocardial Infarction after Irradiation in Hodgkin’s Disease: A Review

      • H. Joensuu
      Pages 157-173

  5. Radiation Induced Sequelae of the Central Nervous System (CNS) and the Eye

    1. Experimental Radiation Damage of the Central Nervous System

      • W. Calvo
      Pages 175-188

    2. Myelopathy and Hyperfractionated Accelerated Radiotherapy: A Radiobiological Interpretation

      • C. S. Wong, J. Van Dyk, R. P. Hill
      Pages 189-197

    3. Irradiation-Induced Brain Dysfunction in Children

      • R. Korinthenberg
      Pages 199-207

    4. Central Nervous System Injury from Implanted Isotopes

      • C. B. Ostertag
      Pages 209-217

    5. Long-Term Cerebral Side-Effects of Total Body Irradiation and Quality of Life

      • M. Peper, P. Schraube, B. Kimmig, C. Wagensommer, M. Wannenmacher, R. Haas
      Pages 219-230
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Keywords

About this book

Biologists and radiotherapists present their experimental work and clinical data in the field of radiation injuries of normal tissues and organs. Particular regard is payed to the relevance of biological mechanisms in clinical situations. Principles of radiation damage and combined treatment toxicity in radio-chemotherapy are being explained. The main topics discussed are the importance of microvasculature, time, doseand fractionation and factors modifying clinical radioresponse for early andlate radiation effects. Tissues and organs considered in this volume are mucosa and skin, lung and heart, bladder and muscle, CNS and eye. Special problems of pediatric radiotherapy, TBI, IORT and second malignacies are also mentioned.

Editors and Affiliations

  • Abteilung Strahlentherapie, Radiologische Universitätsklinik, Freiburg, Germany

    Wolfgang Hinkelbein, Gregor Bruggmoser, Hermann Frommhold

  • Abteilung Radiologie, Radiologische Universitätsklinik, Heidelberg, Germany

    Michael Wannenmacher

Bibliographic Information

  • Book Title: Acute and Long-Term Side-Effects of Radiotherapy

  • Book Subtitle: Biological Basis and Clinical Relevance

  • Editors: Wolfgang Hinkelbein, Gregor Bruggmoser, Hermann Frommhold, Michael Wannenmacher

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-84892-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1993

  • Softcover ISBN: 978-3-642-84894-0Published: 15 December 2011

  • eBook ISBN: 978-3-642-84892-6Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XII, 284

  • Topics: Radiotherapy, Oncology

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