Targeted Intraoperative Radiotherapy in Oncology

1. Front Matter

   Pages i-xiii

   PDF

2. Targeted Intraoperative Radiotherapy: Concept and Review of Evidence in Breast Cancer

   • Mohammed Keshtgar, Frederik Wenz

   Pages 1-6

3. Mechanism of Action of TARGIT

   • Gustavo Baldassarre, Barbara Belletti, Mario Mileto, Samuele Massarut

   Pages 7-12

4. How to Use the INTRABEAM System

   • Regina Gonzalez, Claire Reynolds

   Pages 13-29

5. Quality Assurance and Commissioning

   • Frank Schneider, Sven Clausen, David J. Eaton

   Pages 31-36

6. Radiation Protection

   • David J. Eaton, Frank Schneider

   Pages 37-43

7. Radiobiology

   • Frederik Wenz, Katia Pasciuti, Carsten Herskind

   Pages 45-52

8. Surgical Aspects of the TARGIT Technique in Breast Cancer

   • Mohammed Keshtgar

   Pages 53-66

9. Follow-Up Findings in the Tumour Bed After IORT – What the Radiologist Needs to Know

   • Klaus Wasser, Elena Sperk

   Pages 67-70

10. Quality of Life and Late Radiation Toxicity

    • Elena Sperk, Grit Welzel

    Pages 71-78

11. Cosmetic Outcome Following TARGIT

    • Norman R. Williams, Mohammed Keshtgar

    Pages 79-83

12. Targeted Intraoperative Radiotherapy and Persistent Pain After Treatment

    • Kenneth Geving Andersen, Henrik Flyger

    Pages 85-91

13. Other Applications of INTRABEAM®

    • Tina Reis, Elena Sperk, Yasser Abo-Madyan, Michael Ehmann, Frederic Bludau, Frederik Wenz

    Pages 93-104

14. Intraoperative Photon Radiosurgery in Patients with Malignant Brain Tumours

    • Sam Eljamel

    Pages 105-111

15. Intraoperative Radiotherapy with Low-Energy Photons in Rectal Cancer Recurrence

    • Magdalena Skórzewska, Wojciech P. Polkowski

    Pages 113-118

16. Case Reports

    • Katharine Pigott, Frederik Wenz, Mohammed Keshtgar, Sam Eljamel, Wojciech P. Polkowski, Tina Reis et al.

    Pages 119-133

17. Intra Operative Radiotherapy in Developing Countries: Experience with TARGIT from University of Dammam, Saudi Arabia

    • Maha Abdel Hadi, Mohammed Keshtgar

    Pages 135-139

18. Treating Patients with TARGIT

    • Norman R. Williams, Claire Reynolds

    Pages 141-145

19. Patient Selection and Information

    • Claire Reynolds, Elena Sperk

    Pages 147-152

20. Quality Assurance and Training of Targeted Intraoperative Radiotherapy: Establishment of the TARGIT Academy

    • Mohammed Keshtgar, Frederik Wenz

    Pages 153-156

Targeted intraoperative radiotherapy is a major advance in the management of cancer patients and has been attracting massive interest worldwide following publication of the results of an important randomized controlled trial in The Lancet. This textbook is designed to introduce this innovative technology in a comprehensive manner to clinicians dealing with cancer patients. Throughout, the emphasis is on practical aspects and the text is supported by many excellent illustrations. The editors of the book have extensive experience in targeted intraoperative radiotherapy and include co-directors of the TARGIT Academy, which runs international training courses on the technology in the United Kingdom and Germany. They have brought together multidisciplinary contributors from different centers across the world who have wide experience in the field and whose work has been recognized internationally. It is the editors’ hope that this book will succeed in ensuring that targeted intraoperative radiotherapy is used effectively worldwide.

• Cancer Management
• Cancer Treatment
• Intrabeam System
• TARGIT
• Targeted Intra-Operative Radiotherapy
• Radiaton Oncology
• surgical oncology

“Targeted Intraoperative Radiotherapy in Oncology was written by a multidisciplinary panel of experts who have been involved in the development of TARGIT for many years. … this book is easy to read, focused, and accessible to a broad audience. There are chapters of specific interest to radiologists, oncologists, surgeons, radiation oncologists, and physicists.” (Cory Donovan and Charlotte Dai Kubicky, Journal of Radiation Oncology, Vol. 4, 2015)

• Department of Surgery, Royal Free Hospital, London, United Kingdom

  Mohammed Keshtgar

• Department of Radiation Oncology, Royal Free Hospital, London, United Kingdom

  Katharine Pigott

• University of Heidelberg, University Medical Center Mannheim, Mannheim, Germany

  Frederik Wenz

Policies and ethics