Functional BOLD MRI

This book presents the basic principles and new and emergent clinical applications of BOLD fMRI. It describes the physical principles of BOLD fMRI imaging and reviews scanning methodologies, data analysis, challenges and limitations of BOLD fMRI, neurovascular uncoupling, and functional connectivity. The book also explores current and future clinical applications of BOLD fMRI in the fields of language, memory, fMRI WADA, visual pathway, brain mapping of eloquent cortex, pediatrics, auditory pathways, epilepsy, psychiatric disorders, neurodegenerative disorders, pharmacological applications, and cognitive neuroscience. It concludes with a discussion of BOLD fMRI paradigms that can be used for clinical and cognitive experiments. Derived from Faro, Mohamed, Law, and Ulmer’s Functional Neuroradiology: Principles and Applications, this book is a valuable resource for neurologists, cognitive neuroscientists, and neuroradiologists.

• BOLD functional MRI
• brain mapping
• fMRI
• functional magnetic resonance imaging
• neurovascular uncoupling
• Diagnostic Radiology

“The book has a few chapters comprehensively covering the methods and physical principles of the technique, written by leading researchers in the field, but moves on to the practical challenges of performing functional MRI in the clinic. … An appealing and highly useful feature is the consistent use of tables referencing key papers relevant to that chapter, highlighting their key findings. … a comprehensive text on the topic of clinical fMRI this is an excellent read.” (Dr. Stuart Clare, RAD Magazine, November, 2015)

“This comprehensive introductory book on the principles and application of fMRI … is a welcome addition to the neuroscience literature. … The target audience includes physicians, psychiatrists, and neurologists, as well as trainees in these areas. … This is an excellent introductory book on BOLD fMRI. … Anyone who would like to attain basic fluency in this important research and clinical tool should read this outstanding book.” (Michael Joel Schrift, Doody's BookReviews, April, 2015)

• Department of Radiology, Temple University School of Medicine, Philadelphia, USA

  Scott H. Faro, Feroze B. Mohamed

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