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  • © 2014

Treatment–Refractory Schizophrenia

A Clinical Conundrum

  • Comprehensive, clinically focused guide to the treatment of the most severely ill patients with schizophrenia

  • Informed by the latest research findings on neurobiology and treatment

  • Written by leading experts from Europe and the Americas

  • Includes supplementary material: sn.pub/extras

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
  2. Treatment-Refractory Schizophrenia: Definition and Assessment

    • Derek K. Tracy, Sukhwinder S. Shergill
    Pages 1-19
  3. Dopamine and the Biology and Course of Treatment Resistance

    • Arsime Demjaha, Oliver D. Howes
    Pages 31-43
  4. Overview of Pharmacological Treatments and Guidelines

    • Siobhan Gee, David Taylor
    Pages 65-80
  5. Therapeutic Brain Stimulation in Treatment-Resistant Schizophrenia

    • Peter B. Rosenquist, Anthony O. Ahmed, W. Vaughn McCall
    Pages 107-120
  6. Cognitive Therapies for Refractory Schizophrenia

    • Andrew Watson, Matteo Cella, Til Wykes
    Pages 121-137
  7. Cognitive Behavioural Therapy for Psychosis

    • Elaine C. M. Hunter, Louise C. Johns, Juliana Onwumere, Emmanuelle Peters
    Pages 139-164
  8. Vocational Rehabilitation for Severe Mental Illness

    • Susan R. McGurk, Kim T. Mueser
    Pages 165-177
  9. Pharmacogenetics and Treatment-Resistant Schizophrenia

    • Adriana Foster, Peter F. Buckley
    Pages 179-193
  10. Family Interventions in Psychosis

    • Juliana Onwumere, Elaine Hunter, Elizabeth Kuipers
    Pages 195-223
  11. Back Matter

    Pages 225-230

About this book

Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population  - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care.

In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused  book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.

Reviews

“This book is an excellent collection of chapters that collectively comprise the clinical and scientific knowledge base about refractory schizophrenia. … For psychiatric practitioners, both prescribers and therapists, who manage schizophrenia on a daily basis, this book is a must own reference because of the wealth of helpful information between the covers.” (Henry A. Nasrallah, Journal of Clinical Psychiatry, Vol. 76 (9), September, 2015)

“This interesting book reviews treatment strategies and management options for those suffering from treatment-refractory schizophrenia (TRS). … The target audience includes psychiatrists and other mental health professionals. Any clinicians who treat severely ill patients with psychiatric disorders would benefit from reading this book. … This is an exceptional book covering a current critical issue for psychiatry and the patients suffering from unremitting psychosis. I highly recommend it.” (Michael Joel Schrift, Doody’s Book Reviews, July, 2014)

Editors and Affiliations

  • Medical College of Georgia Dean’s Office, Georgia Regents University, Augusta, USA

    Peter F. Buckley

  • Department of Psychosis Studies, Institute of Psychiatry, National Psychosis Unit, London, United Kingdom

    Fiona Gaughran

Bibliographic Information

  • Book Title: Treatment–Refractory Schizophrenia

  • Book Subtitle: A Clinical Conundrum

  • Editors: Peter F. Buckley, Fiona Gaughran

  • DOI: https://doi.org/10.1007/978-3-642-45257-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2014

  • Hardcover ISBN: 978-3-642-45256-7Published: 01 April 2014

  • Softcover ISBN: 978-3-662-52387-2Published: 23 August 2016

  • eBook ISBN: 978-3-642-45257-4Published: 18 March 2014

  • Edition Number: 1

  • Number of Pages: VIII, 230

  • Number of Illustrations: 1 b/w illustrations, 6 illustrations in colour

  • Topics: Psychiatry, Clinical Psychology

Buy it now

Buying options

Softcover Book USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access