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Medicine - Pathology | Pediatric and Developmental Pathology

Pediatric and Developmental Pathology

Pediatric and Developmental Pathology

Editor-in-Chief: Miguel Reyes-Mugica

ISSN: 1093-5266 (print version)
ISSN: 1615-5742 (electronic version)

Journal no. 10024

Instructions for Authors

Pediatric and Developmental Pathology

Electronic Submission 

Pediatric and Developmental Pathology is now accepting electronic submission of manuscripts through Manuscript Central. We encourage all authors to explore use of this medium for proficient review and submission process. If you are interested in the online submission please visit our link with Manuscript Central at http://mc.manuscriptcentral.com/pdp and follow the screen prompts. We expect that you will appreciate this new and exciting convenience.
  • Netscape 4.x or MS Internet Explorer 4.x/5.x
  • Adobe Acrobat browser plug-in
  • Electronic files of their article text
  • Electronic files of their article graphics (scanned or exported)
Authors entering the journal's Manuscript Central site can either create a new account or use an existing one. When you have an existing account, use it for all your submissions and you can track their status on the same page.
Once you have logged into your account, Manuscript Central will lead you through the submission process in a step-by-step orderly process. If you cannot finish your submission in one visit, you can save a draft and re-enter the process at the same point for that manuscript.
While submitting your electronic manuscript, you will be required to enter data about your manuscript in the system. These include title, subtitle, author names and affiliations, and so forth. Support for special characters is available. At any point during this process, there are Help buttons available to see common questions and a support link to ask a specific question via email.
Electronic files can be uploaded as PDF, PostScript, or RTF. PDF and PostScript files should already contain the graphics within the file. (PostScript files are converted by the system into PDF so that Editors and reviewers may share them.
RTF (Rich Text Format) is a common export property of most popular word processors. Check your word processor to see if it can export or "SaveAs" your file in RTF format. MS Word and WordPerfect both contain this function. After uploading the RTF for text, you will be prompted for uploading graphics. Common graphics files such as GIF, JPEG, EPS, TIFF and many others are supported. After uploading the parts of the article in this manner, the system will convert the files to PDF. You will see the result of the conversion with the Acrobat plug-in in your browser. Keep copies of your word-processing and graphics files. You may want to revise the manuscript during the review process and you will need the original files if your manuscript is accepted. At any point during this process, there are Help buttons available to see common questions and a support link to ask a specific question via email.
You will also be notified by email that your submission was successful.
If you are submitting electronic graphics that you have scanned, be prepared to send the hard copy originals upon request. While the electronic files you have created are satisfactory for the review process, they may not be of sufficient quality for printing. This also holds true for files created in low-resolution graphics environments such as MS Powerpoint, etc.
After submission, you may return periodically and monitor the progress of your submission through the review process.


Send three copies of the manuscript, three full sets of figures (including one suitable for publication), a diskette version, and a cover letter, to:
Miguel Reyes-Múgica
Department of Pathology
Yale University School of Medicine
430 Congress Avenue
New Haven, CT 06519-1402, USA
Tel: (203) 737-5383
Fax: (203) 737-5388
email: peddev.path@yale.edu

Organization of Manuscripts 

MANUSCRIPTS, including references, should be typed on one side of 8 1/2 x 11 paper with double spacing and broad margins, in the order indicated:
TITLE PAGE. The first page must contain a concise title, the complete names of all authors and their departmental and institutional affiliations and complete mailing addresses,addreaddresses, and a separate listing of the name, address, telephone and fax numbers, and email address of the corresponding author as well as the full address of the institution at which the work was performed. If there are more than six authors, the specific contribution of each must be indicated in the cover letter. Also provide a running head (not to exceed 40 characters), and indicate any acknowledgments of grant support.
ABSTRACT. An abstract of not more than 250 words should be placed on a separate page immediately following the title page. It should be a factual, not descriptive, statement of study objectives, methods, principal results, and conclusions. Include up to six key words in alphabetical order. Use Index Medicus terms from medical subject headings where possible.
TEXT. The text should be organized into an Introduction, including the background and purpose of the study, and then into Methods, Results, and Discussion.
ACKNOWLEDGEMENTS. A brief statement on a separate page should acknowledge individuals who were of direct help in the reported work, immediately following the text.
REFERENCES. References must be typed double-spaced and be numbered in the order of citation in the text. Once a reference has been cited, all subsequent citations should be to the original number. All references must be cited in the text or tables. Unpublished data and personal communications are not acceptable references. Papers that have been accepted but not yet published are acceptable as along as a preprint accompanies the manuscript. All references must be verified against the original documents. Abbreviations of journals must conform to the list of journals indexed in Index Medicus. Follow the Vancouver convention for citation:
  • JOURNALS. References to journal article should include surnames and initials (list all authors if fewer than seven; if seven or more, list the first three followed by et al.), full article title, abbreviated journal name, year, volume, and inclusive pagination. An example follows:
    Hussong JW, Perkins SL, Huff V, et al. Familial Wilms' tumor with neural elements: characterization by histology, immunohistochemistry, and genetic analysis. Pediatr Dev Pathol 2000;3:561-567.
  • BOOKS. References to a book should include surnames and initials of author(s), title of book, edition, city, publisher, and year. An example follows:
    Kleihues P, Burger PC, Scheithauer BW. Histological Typing of Tumors of the Central Nervous System, 2nd ed. Berlin, Heidelberg: Springer-Verlag, 1993.
  • CHAPTER IN A BOOK. References to a book should include surnames and initials of author(s), chapter title, editor(s), book title, city, publisher, year, volume, section (if applicable), and inclusive pagination. An example follows:
    Thurlbeck WM. Respiratory System. In: Dimmick JE, Kalousek DK, eds. Developmental Pathology of the Embryo and Fetus. Philadelphia: J.B. Lippincott, 1992;437-466.
  • PAPERS IN CONFERENCE PROCEEDINGS OR ABSTRACTS. These references should include surnames and initials of author(s), title, name of conference, city, publisher, year, and inclusive pagination. Examples follow:
    Kjaer I. The prenatal axial skeleton as marker of normal and pathological development of the human central nervous system. In: Alfred Benzon Symposium: Brain Lesions in the Newborn. Copenhagen: Munksgaard, 1994;37:124-132.
    Polendo R, Lowe GN, McDougall S, Hahn TJ. Mechanism of prostaglandin regulation of proteoglycan synthesis in rat chondrocytic cells (abstract). J Bone Miner Res 1994;9:S187.
TABLES. Each table should be typed double spaced on a separate page, numbered consecutively, and given a brief title; all tables must be cited in the text.
FIGURES. Legends for figures should be typed double spaced beginning on a separate page. All figures must be cited in the text. Figures should be professionally drawn and/or photographed, submitted as black and white high-quality glossy prints. Special attention should be paid to contrast and focus. Do not submit original art. Symbols and numbers must be of sufficient size and contrast to be clearly recognizable when the figures is reduced to publication size. Label the back of each figure with its number, name of first author, and preferred orientation. Optimal size for figures is 8.5 x 10 cm (3 1/4 x 4 in). Figures submitted in electronic form must be accompanied by glossy prints. Submit tiff and Illustrator eps files of high resolution on ZIP or floppy disks.
We encourage the submission of supplemental materials to be made available for retrieval by readers in the online version of the journal. Videos and other lengthy materials not suitable for printed publication may also be submitted for possible inclusion on the journal's web site, LINK. A limited number of color illustrations will be considered for publication with a text article, but the author may be required to bear some or all of the cost. The cost structure for color figures is as follows: $575 for one color figure. Color can be used without charge for the electronic edition. Artwork to accepted manuscripts will not be returned unless a written request accompanies the page proofs.
ABBREVIATIONS, SPELLINGS, AND UNITS. Standard abbreviations and units listed in Scientific Style and Format: The CBE Manual for Authors, Editors, and Publishers, Sixth Edition, Reston, VA: Council of Biology Editors, 1994, should be used. All quantitative measurements should be in conventional metric units, followed when appropriate by the SI unit in parentheses (Clin Chem 25: 657-658, 1979. National Committee of Clinical Laboratory Standards Position Paper PPC-11, 1979).
PERMISSIONS. Copyrighted material from other sources must be accompanied by written permission from both the publisher and author. Any personal communication used in the text must be accompanied by a letter of agreement for use of text as written.
REVIEW PROCESS. The Editor-in-Chief will assign at least two experts in the field to review each manuscript. The reviewer evaluations and the comments of the Editor will be compiled for transmission to the author. Every effort is made to complete the review process within 45 days of the date received.
CASE REPORTS. Limit abstracts to 150 words, use no more than three tables or figures and limit references to 15. Additional illustrations may be submitted for online storage and retrieval.
LETTERS TO THE EDITOR. Letters to the editor intended for publication should not exceed 800 words in length. Up to three references and two illustrations may accompany the letter. Letters must include the name, departmental and institutional affiliations and complete mailing addresses of the authors. The editorial board reserves the right to accept, reject, or excerpt letters without changing the views expressed by the author.
REPRINTS. Reprints may be purchased through an agent of the publisher; instructions will be sent with the page proofs. Individual reprints of an article must be obtained from the author.

Guidelines for Electronically Produced Illustrations for Print 

  • Send illustrations separately from the text (i.e. files should not be integrated with the text files). Always send printouts of all illustrations.
  • Vector graphics exported from a drawing program should be stored in EPS format.
  • Suitable drawing program: Adobe Illustrator. For simple line art the following drawing programs are also acceptable: Corel Draw, Freehand, Canvas.
  • No rules narrower than .25 pt.
  • No gray screens paler than 15% or darker than 60%.
  • Screens meant to be differentiated from one another must differ by at least 15%.
  • Most presentation programs (Excel, PowerPoint, Freelance) produce data that cannot be stored in an EPS format. Therefore graphics produced by these programs cannot be used for print.
  • Black & white and color illustrations should be saved in TIFF format.
  • Illustrations should be created using Adobe Photoshop whenever possible.
  • Scanned reproductions of black and white photographs should be provided as 300 ppi TIFF files.
  • Scanned color illustrations should be provided as TIFF files scanned at a minimum of 300 ppi with a 24-bit color depth.
  • Line art should be provided as TIFF files at 600 ppi.
* We do prefer having the original art as our printers have drum scanners which allow for better reproduction of critical medical halftones.
  • Separate files should be prepared for frames from a video that are to be printed in the journal. When preparing these files you should follow the same rules as listed under Halftone Illustrations.

English Language Editing 

For editors and reviewers to accurately assess the work presented in your manuscript you need to ensure the English language is of sufficient quality to be understood. If you need help with writing in English you should consider:
  • Asking a colleague who is a native English speaker to review your manuscript for clarity.
  • Visiting the English language tutorial which covers the common mistakes when writing in English.
  • Using a professional language editing service where editors will improve the English to ensure that your meaning is clear and identify problems that require your review. Two such services are provided by our affiliates Nature Research Editing Service and American Journal Experts. Springer authors are entitled to a 10% discount on their first submission to either of these services, simply follow the links below.
Please note that the use of a language editing service is not a requirement for publication in this journal and does not imply or guarantee that the article will be selected for peer review or accepted.
If your manuscript is accepted it will be checked by our copyeditors for spelling and formal style before publication.


● 请一位以英语为母语的同事审核您的稿件是否表意清晰。
● 查看一些有关英语写作中常见语言错误的教程。
● 使用专业语言编辑服务,编辑人员会对英语进行润色,以确保您的意思表达清晰,并识别需要您复核的问题。我们的附属机构 Nature Research Editing Service 和合作伙伴 American Journal Experts 即可提供此类服务。


・プロの英文校正サービスを利用する。校正者が原稿の意味を明確にしたり、問題点を指摘し、英語の質を向上させます。Nature Research Editing Service とAmerican Journal Experts の2つは弊社と提携しているサービスです。Springer の著者は、いずれのサービスも初めて利用する際には10%の割引を受けることができます。以下のリンクを参照ください。


영어 원고의 경우, 에디터 및 리뷰어들이 귀하의 원고에 실린 결과물을 정확하게 평가할 수 있도록, 그들이 충분히 이해할 수 있을 만한 수준으로 작성되어야 합니다. 만약 영작문과 관련하여 도움을 받기를 원하신다면 다음의 사항들을 고려하여 주십시오:
• 귀하의 원고의 표현을 명확히 해줄 영어 원어민 동료를 찾아서 리뷰를 의뢰합니다.
• 영어 튜토리얼 페이지에 방문하여 영어로 글을 쓸 때 자주하는 실수들을 확인합니다.
• 리뷰에 대비하여, 원고의 의미를 명확하게 해주고 리뷰에서 요구하는 문제점들을 식별해서 영문 수준을 향상시켜주는 전문 영문 교정 서비스를 이용합니다. Nature Research Editing Service와 American Journal Experts에서 저희와 협약을 통해 서비스를 제공하고 있습니다. Springer 저자들이 본 교정 서비스를 첫 논문 투고를 위해 사용하시는 경우 10%의 할인이 적용되며, 아래의 링크를 통하여 확인이 가능합니다.
영문 교정 서비스는 게재를 위한 요구사항은 아니며, 해당 서비스의 이용이 피어 리뷰에 논문이 선택되거나 게재가 수락되는 것을 의미하거나 보장하지 않습니다.
원고가 수락될 경우, 출판 전 저희측 편집자에 의해 원고의 철자 및 문체를 검수하는 과정을 거치게 됩니다.

Guidelines for Electronically Produced Illustrations for ONLINE 

  • Quicktime (.mov) is the preferred format, but .rm, .avi, .mpg, etc. are acceptable.
  • No video file should be larger than 2MB. To decrease the size of your file, consider changing one or more of the following variables: frame speed, number of colors/greys, viewing size (in pixels), or compression. Video is subject to Editorial review and approval.

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For authors and editors

  • Aims and Scope

    Aims and Scope


    Pediatric and Developmental Pathology is designed for the timely communication of peer-reviewed studies which provide significant new information or insights into the pathophysiology of the developing human embryo, fetus, and child. Contributions are reviewed and selected by a group of distinguished referees from around the world, some of whom constitute the journal's Editorial Board. The journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information. Each issue includes one current, comprehensive review article of a critical topic in pediatric pathology, solicited, reviewed, and edited by the Editorial Board of "Perspectives."

    Editorials, biographical sketches, historical notes, annotated bibliographies, updates on pediatric cancer protocols, book reviews, laboratory or practice management, and letters are published at the discretion of the Editor-in-Chief. Appropriately peer-reviewed abstracts of pediatric pathology meetings are published by prior arrangement between the society sponsoring the abstracts and the Society for Pediatric Pathology's Publications Committee.

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    Copyright Information




    Submission of a manuscript implies: that the work described has not been published before (except in the form of an abstract or as part of a published lecture, review or thesis); that it is not under consideration for publication elsewhere; that its publication has been approved by all coauthors, if any, as well as, tacitly or explicitly, by the responsible authorities at the institution where the work was carried out. Transfer of copyright to Society for Pediatric Pathology becomes effective if and when the article is accepted for publication. The copyright covers the exclusive right (for U.S. government employees: to the extent transferable) to reproduce and distribute the article, including reprints, translations, photographic reproductions, microform, electronic form (offline, online) or other reproductions of similar nature.

    All articles published in this journal are protected by copyright, which covers the exclusive rights to reproduce and distribute the article (e.g., as reprints), as well as all translation rights. No material published in this journal may be reproduced photographically or stored on microfilm, in electronic data bases, video disks, etc., without first obtaining written permission from Society for Pediatric Pathology. The use of general descriptive names, trade names, trademarks, etc., in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

    An author may self-archive an author-created version of his/her article on his/her own website and his/her institution’s repository, including his/her final version; however he/she may not use the publisher’s PDF version which is posted on www.springerlink.com. Furthermore, the author may only post his/her version provided acknowledgement is given to the original source of publication and a link is inserted to the published article on Springer’s website. The link must be accompanied by the following text: "The original publication is available at www.springerlink.com".

    Please use the appropriate DOI for the article (go to the Linking Options in the article, then to OpenURL and use the link with the DOI). Articles disseminated via www.springerlink.com are indexed, abstracted, and referenced by many abstracting and information services, bibliographic networks, subscription agencies, library networks, and consortia.

    While the advice and information in this journal is believed to be true and accurate at the date of its publication, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Springer-Verlag publishes advertisements in this journal in reliance upon the responsibility of the advertiser to comply with all legal requirements relating to the marketing and sale of products or services advertised. Springer-Verlag and the editors are not responsible for claims made in the advertisements published in the journal. The appearance of advertisements in Springer-Verlag publications does not constitute endorsement, implied or intended, of the product advertised or the claims made for it by the advertiser.

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