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Pathology of the Nucleus

  • Book
  • © 1990

Overview

Editors:
  1. James C. E. Underwood

    1. Department of Pathology, University of Sheffield Medical School, Sheffield, UK

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Part of the book series: Current Topics in Pathology (CT PATHOLOGY, volume 82)

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Table of contents (7 chapters)

  1. Front Matter

    Pages I-IX
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  2. Nuclear Morphology and Grading in Tumours

    • J. C. E. Underwood
    Pages 1-15

  3. Ultrastructural Pathology of the Nucleus

    • H. M. H. Kamel, J. Kirk, P. G. Toner
    Pages 17-89

  4. Nucleolar Organiser Regions

    • J. Crocker
    Pages 91-149

  5. Quantitation of the Nucleus

    • T. J. Stephenson
    Pages 151-213

  6. Flow Cytometry in the Quantitation of DNA Aneuploidy and Cell Proliferation in Human Disease

    • P. Quirke
    Pages 215-256

  7. Karyotypic Analysis of Solid Tumors

    • P. Dal Cin, A. A. Sandberg
    Pages 257-288

  8. Techniques and Applications of In Situ Hybridisation

    • G. Terenghi, R. A. Fallon
    Pages 289-337

  9. Back Matter

    Pages 339-346
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Keywords

About this book

New techniques make it possible for investigators to examine and sometimes quantify various aspects of nuclear morphology and function; now they can derive clinically and biologically useful information about the nucleus. This book draws together a series of techniques which have been successfully applied to the study of the nucleus of tumour cells. These are of fundamental importance to researchers in tumour histopathology and medical oncology. Detailed reviews are given of various aspects of the morphology, ploidy and karyotypic status and function of the nuclei in the cells of tumours and preneoplastic lesions. Topics covered include nuclear morphology in tumour diagnosis, the ultrastructure of the nucleus, karyotypic analyses of solid tumours, flow cytometric assessment of nuclear ploidy and other parameters, histomorphometry of the nucleus, and in situ hybridisation.

Editors and Affiliations

  • Department of Pathology, University of Sheffield Medical School, Sheffield, UK

    James C. E. Underwood

Bibliographic Information

  • Book Title: Pathology of the Nucleus

  • Editors: James C. E. Underwood

  • Series Title: Current Topics in Pathology

  • DOI: https://doi.org/10.1007/978-3-642-74668-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1990

  • Softcover ISBN: 978-3-642-74670-3Published: 13 December 2011

  • eBook ISBN: 978-3-642-74668-0Published: 06 December 2012

  • Series ISSN: 0070-2188

  • Edition Number: 1

  • Number of Pages: IX, 343

  • Topics: Pathology, Oncology, Cell Biology

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