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  • © 2012

Translational Cardiology

Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques

  • New developments in cellular, viral, and non-biologic therapies
  • All chapters are written by experts with diverse backgrounds
  • Focus on patient-oriented disease mechanisms and therapies
  • The authors simplify complex concepts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Molecular and Translational Medicine (MOLEMED)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xv
  2. Relationship Between Myocardial Ischemia/Reperfusion and Time of Day

    • David J. Durgan, Martin E. Young
    Pages 1-38
  3. Phosphotransfer Reactions in the Failing Heart

    • Joanne S. Ingwall
    Pages 39-62
  4. Mitochondria in Cardiac Disease

    • Roberta A. Gottlieb, GioVanni Quarato, E. Dale Abel
    Pages 63-82
  5. PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease

    • Jennifer G. Duncan, Brian N. Finck
    Pages 83-111
  6. AMPK and Metabolic Remodeling in Cardiac Disease

    • Thomas Pulinilkunnil, Jeevan Nagendran, Jason R. B. Dyck
    Pages 113-150
  7. Mechanotransduction in Cardiac Hypertrophy and Ischemia

    • Miensheng Chu, Yevgeniya E. Koshman, Allen M. Samarel
    Pages 151-184
  8. Cardiac Plasticity in Health and Disease

    • Raj B. Gondalia, Beverly A. Rothermel, Sergio Lavandero, Thomas G. Gillette, Joseph A. Hill
    Pages 185-250
  9. Ubiquitylation - Dependent Signaling in Heart Disease

    • Monte S. Willis, Andrea Portbury, Sarah Ronnebaum, Makhosazane Zungu, W. H. Davin Townley-Tilson, Cam Patterson
    Pages 251-289
  10. Mechanisms of Cardiac Dysfunction Associated with Cancer Therapeutics

    • Vishnu Chintalgattu, Aarif Y. Khakoo
    Pages 291-316
  11. Cellular Therapy for the Infarcted Myocardium

    • S. C. Den Hartogh, J. P. Sluijter, P. A. Doevendans, L. W. Van Laake
    Pages 341-390
  12. Molecular Imaging of Cardiovascular Disease

    • Patricia K. Nguyen, Divya Nag, Joseph C. Wu
    Pages 485-531
  13. Back Matter

    Pages 533-543

About this book

Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

Reviews

From the reviews:

“This is an introduction to evolving concepts in biochemical and cellular signaling pathways in cardiac myocyte metabolism. … The target audience includes students, physicians in training, advanced practice clinicians, and practicing physicians from a variety of specialties involved in treating patients with cardiac disease. … The topics this book covers are evolving and include a broad array of information that introduces many cutting edge concepts. It is a valuable resource that will pave the way for innovative therapeutic methods for cardiac diseases.” (Nay Htyte, Doody’s Review Service, October, 2012)

Editors and Affiliations

  • , The University of North Carolina, McAllister Heart Institute, Chapel Hill, USA

    Cam Patterson, Monte S. Willis

About the editors

Cam Patterson, MD, MBA
McAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA

Monte S. Willis, MD, PhD
McAllister Heart Institute, The University of North Carolina School of Medicine, Chapel Hill, NC, USA

Bibliographic Information

  • Book Title: Translational Cardiology

  • Book Subtitle: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques

  • Editors: Cam Patterson, Monte S. Willis

  • Series Title: Molecular and Translational Medicine

  • DOI: https://doi.org/10.1007/978-1-61779-891-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-890-0Published: 05 July 2012

  • Softcover ISBN: 978-1-62703-934-5Published: 09 August 2014

  • eBook ISBN: 978-1-61779-891-7Published: 04 July 2012

  • Series ISSN: 2197-7852

  • Series E-ISSN: 2197-7860

  • Edition Number: 1

  • Number of Pages: XVI, 544

  • Topics: Pathology, Cardiology, Molecular Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access