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Medicine - Pathology | Biotargets of Cancer in Current Clinical Practice

Biotargets of Cancer in Current Clinical Practice

Bologna, Mauro (Ed.)

2012, XVI, 563p. 100 illus., 57 illus. in color.

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  • Provides the latest information on the validation status of each novel biomarker
  • Covers the present debate on potential clinical use of newly discovered biochemical markers and on patentability of genetic information
  • Chapter authors are experts on the particular cancer type
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.

Content Level » Professional/practitioner

Keywords » Cancer Therapeutics - Epidemiology - Metastasis

Related subjects » Biomedical Sciences - Oncology & Hematology - Pathology

Table of contents 

Ch. 1- Central Nervous System Tumors
 Paolo Aloisi
 Francesco Martella
 Davide Cerone
 Giampiero Porzio
 
Ch. 2- Head and Neck Tumors
 Keith D. Hunter
 Robert Bolt

Ch. 3- Thyroid Cancer
 Laura D. Locati
 Angela Greco
 Maria Grazia Borrello
 Maria Luisa Carcangiu
 Paolo Bossi
 Roberta Granata
 Lisa Licitra

Ch. 4- Targeted Therapies for Non-Small Cell Lung Cancer
 Giulio Metro
 Lucio Crinò

Ch. 5- Non-Hodgkin Lymphomas
 Roberta Zappasodi
 Massimo Di Nicola

Ch. 6- Leukemias
 Lia Ginaldi 
 Massimo De Martinis

Ch. 7- Breast Cancer
 Nadia Rucci
 Luca Ventura
 Anna Teti

Ch. 8- Esophago-Gastric Cancer
 Alex M. Reece-Smith
 Simon L. Parsons 
 Sue A. Watson

Ch. 9- Colorectal Cancer
 David Church
 Rachel Midgley
 David Kerr

Ch. 10- Hepatocellular Carcinoma
 Yasunori Minami
 Masatoshi Kudo

Ch. 11- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma
 Laura S. Schmidt

Ch. 12- Bladder Cancer
 Andrea Tubaro
 Daniele Santini
 Cosimo De Nunzio
 Alice Zoccoli
 Michele Iuliano

Ch. 13- Biomarkers in Prostate cancer
 Mauro Bologna
 Carlo Vicentini

Ch. 14- Ovarian Cancer
 Jessica Wangui Oribabor
 Allison Ambrosio
 Cesar M. Castro
 Michael J. Birrer

Ch. 15- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer
 Annekathryn Goodman
 Leslie S. Bradford
 Leslie A. Garrett


Ch. 16- Biotargets in Sarcomas: The Past, Present and a Look into the Future
 Vivek Subbiah
 Razelle Kurzrock

Ch. 17- Melanoma and other skin cancers
 Kim H.T. Paraiso
 Jobin K. John
 Keiran S.M. Smalley

Ch. 18- Molecular pathology of cancer metastasis: suggestions for future therapy
 Adriano Angelucci
 Edoardo Alesse

Ch. 19- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools
 Marilena V. Iorio
 Patrizia Casalini
 Claudia Piovan
 Luca Braccioli
 Elda Tagliabue

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