Biotargets of Cancer in Current Clinical Practice

1. Front Matter

   Pages i-xvi

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2. Central Nervous System Tumors

   • Paolo Aloisi, Francesco Martella, Davide Cerone, Giampiero Porzio

   Pages 1-18

3. Head and Neck Tumours

   • Keith D. Hunter, Robert Bolt

   Pages 19-59

4. Thyroid Cancer

   • Laura D. Locati, Angela Greco, Maria Grazia Borrello, Maria Luisa Carcangiu, Paolo Bossi, Roberta Granata et al.

   Pages 61-91

5. Targeted Therapies for Non-small-Cell Lung Cancer

   • Giulio Metro, Lucio Crinò

   Pages 93-114

6. Non-Hodgkin’s Lymphomas

   • Roberta Zappasodi, Massimo Di Nicola

   Pages 115-157

7. Leukemias

   • Lia Ginaldi, Massimo De Martinis

   Pages 159-194

8. Breast Cancer

   • Nadia Rucci, Luca Ventura, Anna Teti

   Pages 195-219

9. Oesophago-Gastric Cancer

   • Alex M. Reece-Smith, Simon L. Parsons, Sue A. Watson

   Pages 221-244

10. Colorectal Cancer

    • David N. Church, Rachel Susannah Midgley, David J. Kerr

    Pages 245-272

11. Hepatocellular Carcinoma

    • Yasunori Minami, Masatoshi Kudo

    Pages 273-287

12. Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma

    • Laura S. Schmidt

    Pages 289-324

13. Bladder Cancer

    • Andrea Tubaro, Daniele Santini, Cosimo De Nunzio, Alice Zoccoli, Michele Iuliano

    Pages 325-354

14. Biomarkers in Prostate Cancer

    • Mauro Bologna, Carlo Vicentini

    Pages 355-380

15. Ovarian Cancer

    • Jessica Wangui Oribabor, Allison Ambrosio, Cesar M. Castro, Michael J. Birrer

    Pages 381-401

16. Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer

    • Annekathryn Goodman, Leslie S. Bradford, Leslie A. Garrett

    Pages 403-417

17. Biotargets in Sarcomas: The Past, Present, and a Look into the Future

    • Vivek Subbiah, Razelle Kurzrock

    Pages 419-438

18. Melanoma and Other Skin Cancers

    • Kim H. T. Paraiso, Jobin K. John, Keiran S. M. Smalley

    Pages 439-468

19. Molecular Pathology of Cancer Metastasis: Suggestions for Future Therapy

    • Adriano Angelucci, Edoardo Alesse

    Pages 469-515

20. Current and Future Developments in Cancer Therapy Research: miRNAs as New Promising Targets or Tools

    • Marilena V. Iorio, Patrizia Casalini, Claudia Piovan, Luca Braccioli, Elda Tagliabue

    Pages 517-546

Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.

• Cancer Therapeutics
• Epidemiology
• Metastasis

From the reviews:

“In this book on clinically significant biotargets in cancer research, every organ system is thoroughly represented with adequate overviews and precise details of the biotargets. … the book is intended specifically for clinicians in the field, including medical students, residents, pathologists, and oncologists. … This is a well-written book that attempts to provide a wide spectrum of current scientific information about the clinical management of oncologic patients based on molecular aspects. … this book achieves its objectives while remaining easy to read.” (Natalie Webster, Doody’s Review Service, October, 2012)

• Chair of General Pathology, Department of Experimental Medicine, University of L’Aquila, L'Aquila, Italy

  Mauro Bologna

Mauro Bologna, MD
University of L’Aquila, L’Aquila, Italy

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