Editors:
- Presents a range of applications for oncological disease
- Useful and comprehensive resource
- Written by international opinion leaders in the field
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Clinical Pathology (CCPATH)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
About this book
Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors.
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Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors.
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Diagnostic, Prognostic and Therapeutic Value of Gene Signatures will be of great value to residents and fellows, physicians, pathologists and medical oncologists.
Reviews
From the reviews:
“This is a useful compendium of various molecular methods (with a special focus on microarray technology) applied to research and diagnostic and prognostic purposes for most solid human tumors … . The book is designed primarily for residents and fellows, oncologists, pathologists, molecular biologists, biotechnologists, and others who study oncologic diseases. … chapters are detailed and informative and present molecular genetic aspects in an appropriate clinical setting. … The references following each chapter are extensive, relevant, and updated.” (Semir Vranic, Doody’s Review Service, July, 2012)Editors and Affiliations
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Department of Surgical and, Oncological Sciences, University of Palermo, Palermo, Italy
Antonio Russo
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, National Consortium for Research on, University D’Annunzio, Chieti, Italy
Stefano Iacobelli
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INSERM U624, Marseille, France
Juan Iovanna
Bibliographic Information
Book Title: Diagnostic, Prognostic and Therapeutic Value of Gene Signatures
Editors: Antonio Russo, Stefano Iacobelli, Juan Iovanna
Series Title: Current Clinical Pathology
DOI: https://doi.org/10.1007/978-1-61779-358-5
Publisher: Humana Totowa, NJ
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-357-8Published: 02 November 2011
Softcover ISBN: 978-1-4939-6259-4Published: 23 August 2016
eBook ISBN: 978-1-61779-358-5Published: 03 November 2011
Series ISSN: 2197-781X
Series E-ISSN: 2197-7828
Edition Number: 1
Number of Pages: XI, 182
Number of Illustrations: 4 b/w illustrations, 24 illustrations in colour
Topics: Pathology, Oncology, Laboratory Medicine