Overview
- Editors:
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Alan H. B. Wu
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San Francisco General Hospital, Clinical Chemistry Lab., University of California, San Francisco, San Francisco, USA
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Kiang-Teck J. Yeo
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Department of Pathology, Clinical Pharmacogenomics Program, University of Chicago, Chicago, USA
- First book to focus on specific tests used in current clinical practice
- Each chapter authored by an expert in the application covered
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Table of contents (16 chapters)
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Basic concepts
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- Kiang-Teck J. Yeo, Nikolina Babic, Alan H. B. Wu
Pages 3-14
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- Nikolina Babic, Loren J. Joseph, Kiang-Teck J. Yeo
Pages 15-34
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- Steven H. Y. Wong, Christopher Happy, Daniel Blinka, Suson Goch, Jeffrey M. Jensen, Joseph M. Donald et al.
Pages 47-56
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Chemotherapeutics
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- R. Stephanie Huang, Federico Innocenti, Mark J. Ratain
Pages 59-75
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- Christine L. H. Snozek, Alicia Algeciras-Schimnich, Matthew P. Goetz, Loralie J. Langman
Pages 77-89
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- Terreia S. Jones, Mary V. Relling
Pages 91-114
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Specific Pharmacogenomic Targets: Cardiovascular Drugs
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Front Matter
Pages 115-115
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Cardiovascular drugs
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- Janice Y. Chyou, Marc S. Sabatine
Pages 139-153
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- Richard L. Seip, Jorge Duconge, Gualberto Ruaño
Pages 155-174
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- H. Robert Superko, Tom White, James Forrester, Spencer King III
Pages 175-198
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Drugs that Cause Delayed Hypersensitivity
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Front Matter
Pages 199-199
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Drugs that cause delayed hypersensitivity
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- Elizabeth J. Phillips, Simon A. Mallal
Pages 201-212
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- Pei Chen, Shuen-Iu Hung, Shih-Yang Chen, Yuan-Tsong Chen
Pages 213-223
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- Shuen-Iu Hung, Wen-Hung Chung, Jing-Jane Tsai, Yuan-Tsong Chen
Pages 225-236
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Miscellaneous Drugs
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Front Matter
Pages 237-237
About this book
While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.
Reviews
From the reviews:
“The book is written for clinical laboratory directors ‘contemplating or assigned the task of establishing a pharmacogenomics laboratory,’ pharmacologists, and interested clinicians who may have to interpret results. This book also would be of interest to … allied health practitioners, regulators, reimbursers, and test device manufacturers. … The writing is concise, clear, and accessible for what might be considered a complex topic. … Get this book if you want a quick, concise, and fascinating read about the current world and use of pharmacogenomic testing.” (Valerie L. Ng, Doody’s Review Service, May, 2011)
Editors and Affiliations
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San Francisco General Hospital, Clinical Chemistry Lab., University of California, San Francisco, San Francisco, USA
Alan H. B. Wu
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Department of Pathology, Clinical Pharmacogenomics Program, University of Chicago, Chicago, USA
Kiang-Teck J. Yeo