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  • © 2014

Molecular Diagnostics

12 Tests That Changed Everything

  • Each chapter focuses on a specific molecular test and provides a comprehensive background on the test and its clinical applications
  • Authored by renowned experts in the field
  • Accompanied by numerous illustrations and color photographs
  • Includes supplementary material: sn.pub/extras

Part of the book series: Molecular and Translational Medicine (MOLEMED)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii
  2. Oncology

    1. Front Matter

      Pages 1-1
    2. Clinical FISH Testing for the Diagnosis of Solid Tumors

      • Benjamin R. Kipp, Kevin C. Halling
      Pages 3-13
    3. The Human Epidermal Growth Factor Receptor 2 (HER2)

      • Laura J. Tafe, Gregory J. Tsongalis
      Pages 23-33
    4. Tamoxifen and Irinotecan Pharmacogenomics

      • John Logan Black III
      Pages 35-54
  3. Infectious Disease

    1. Front Matter

      Pages 55-55
    2. Hepatitis C Virus Testing

      • Hassan M. E. Azzazy, Karim M. Abdel-Hady
      Pages 57-80
    3. Laboratory Testing for HIV Infection: Advances After 28 Years

      • Joseph Ntumbong Nkeze, Niel T. Constantine, Richard Y. Zhao
      Pages 81-106
    4. Detection of Herpes Simplex Virus in Cerebrospinal Fluid Using Real-Time PCR

      • Thomas F. Smith, Mark J. Espy, Matthew J. Binnicker
      Pages 107-119
    5. Toward a Safer Blood Supply: The Impact of Molecular Testing

      • Niel T. Constantine, Patricia A. Wright, Ahmed Saleh, Anna DeMarinis
      Pages 121-145
  4. Genetics

    1. Front Matter

      Pages 147-147
    2. Chromosome Microarrays

      • Umut Aypar, Swaroop Aradhya, Hutton Kearney, Christa Martin, Sarah South, Eric C. Thorland
      Pages 149-165
    3. BRCA1 and BRCA2 Testing in Inherited Breast Cancer

      • Karla R. Bowles, Eric Rosenthal
      Pages 167-189
  5. Future Directions: The Test That Will Change Everything—Again

    1. Front Matter

      Pages 223-223
    2. Next Generation Clinical Diagnostics: The Sequence of Events

      • Nicole Hoppman, David I. Smith, Eric W. Klee, Matthew J. Ferber
      Pages 225-249
  6. Back Matter

    Pages 251-257

About this book

Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients.  Presented as a standard outline, each chapter focuses on a specific molecular test  and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question.

Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.

Reviews

From the reviews:

“This book is intended for molecular pathologists, clinical laboratory directors, genetics/pathology residents/fellows, and clinical laboratory science students. It also would be of great interest to practitioners who use test results from these methodologies in their daily practice -- infectious disease physicians, oncologists, geneticists, neonatologists, obstetricians, etc. -- interested in the technology behind the tests. … This is the book to read if you want a quick, concise, and relatively current update on molecular diagnostic tests that have truly changed medical practice.” (Valerie L. Ng, Doody’s Book Reviews, January, 2014)

Editors and Affiliations

  • Medicine and Pathology Molecular Genetics Laboratory, Mayo Clinic College of Medicine Department of Laboratory, Rochester, USA

    W. Edward Highsmith, Jr.

About the editor

W. Edward Highsmith, Jr., PhD
Mayo Clinic College of Medicine, Department of Laboratory Medicine and Pathology, Molecular Genetics Laboratory, Rochester, MN, USA

Bibliographic Information

  • Book Title: Molecular Diagnostics

  • Book Subtitle: 12 Tests That Changed Everything

  • Editors: W. Edward Highsmith, Jr.

  • Series Title: Molecular and Translational Medicine

  • DOI: https://doi.org/10.1007/978-1-4614-8127-0

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4614-8126-3Published: 20 September 2013

  • Softcover ISBN: 978-1-4939-4265-7Published: 23 August 2016

  • eBook ISBN: 978-1-4614-8127-0Published: 20 September 2013

  • Series ISSN: 2197-7852

  • Series E-ISSN: 2197-7860

  • Edition Number: 1

  • Number of Pages: XIII, 257

  • Number of Illustrations: 6 b/w illustrations, 41 illustrations in colour

  • Topics: Pathology, Oncology, Infectious Diseases

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access