Skip to main content
  • Book
  • © 2012

Modern Clinical Molecular Techniques

  • Presents the essentials of daily laboratory practice

  • Covers oncology testing, pre/post-natal testing, infectious disease testing, and identity testing

  • Details the most up-to-date protocols in molecular pathology

  • Written by the world’s foremost authorities in clinical molecular laboratory science

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (28 chapters)

  1. Front Matter

    Pages i-xiii
  2. Current Molecular Laboratory Methods

    1. Front Matter

      Pages 1-1
    2. Specimen Collection, Handling, and Processing

      • Lindsy Hengesbach, John A. Gerlach
      Pages 3-9
    3. DNA/RNA Isolation and Quantitation

      • Jing Wang
      Pages 11-22
    4. Test Validation

      • Cindy McCloskey, S. Terence Dunn
      Pages 23-47
    5. In Vitro Amplification Methods in Molecular Diagnostics

      • C. Alexander Valencia, Bradford Coffee
      Pages 49-66
    6. Whole Genome Sequencing in the Clinical Laboratory

      • Tina Hambuch, Brad Sickler, Arnold Liao, Suneer Jain, Philip D. Cotter
      Pages 67-78
    7. Reporting Clinical Molecular Genetic Laboratory Results

      • Victor Wei Zhang, Lora J. H. Bean
      Pages 87-93
  3. Clinical Molecular Infectious Disease Testing

    1. Front Matter

      Pages 95-95
    2. HIV-1 Genotyping and Virtual Phenotyping

      • Fangling Xu, Jianli Dong
      Pages 97-121
    3. COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test, Version 2.0

      • Tavat A. Buraruk, Charles E. Stager
      Pages 123-140
    4. Hepatitis C Virus (HCV) Genotype Assay (LiPA)

      • Charles E. Stager, Tavat A. Buraruk
      Pages 141-151
    5. COBAS® AmpliPrep/COBAS® TaqMan® HCV Test

      • Charles E. Stager, Tavat A. Buraruk
      Pages 153-170
    6. Epstein-Barr Virus and Cytomegalovirus Viral Load Monitoring by Quantitative Real-Time Polymerase Chain Reaction

      • Su S. Chen, Seema Hai, Margaret L. Gulley, Rajyalakshmi Luthra
      Pages 171-186
    7. Quantification of BK Viral Load

      • Hai Wu, Jianli Dong
      Pages 187-198
    8. Molecular Diagnosis and Epidemiology of Rabies

      • Rodney E. Rohde, Bonny C. Mayes
      Pages 199-211
    9. Pyrosequencing for Bacterial Identification

      • Laura Millecker, Ruth Ann Luna
      Pages 213-223
    10. Other Pathogens of Significant Public Health Concern

      • Chris L. McGowin, Rodney E. Rohde, Greg C. Whitlock
      Pages 225-241
  4. Clinical Molecular Oncology Testing

    1. Front Matter

      Pages 243-243

About this book

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure.  It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice.

Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Editors and Affiliations

  • , Molecular Genetic Technology Program, M.D. Anderson Cancer Center, Houston, USA

    Peter Hu

  • , Department of Human Genetics, Emory University School of Medicine, Atlanta, USA

    Madhuri Hegde

  • , Molecular Genetic Technology Program, M. D. Anderson Cancer Center, Houston, USA

    Patrick Alan Lennon

Bibliographic Information

  • Book Title: Modern Clinical Molecular Techniques

  • Editors: Peter Hu, Madhuri Hegde, Patrick Alan Lennon

  • DOI: https://doi.org/10.1007/978-1-4614-2170-2

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-2169-6Published: 14 May 2012

  • Softcover ISBN: 978-1-4939-4148-3Published: 23 August 2016

  • eBook ISBN: 978-1-4614-2170-2Published: 11 May 2012

  • Edition Number: 1

  • Number of Pages: XIII, 436

  • Topics: Pathology, Molecular Medicine, Oncology, Infectious Diseases, Health Promotion and Disease Prevention

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access