Cellular Cancer Markers

1. Front Matter

   Pages i-xi

   PDF

2. Clinical Application of Genetic, Oncogenic, and Differentiation Markers of Cancer

   • Stewart Sell, Carleton T. Garrett

   Pages 1-16

3. ras Proto-Oncogene Activation in Human Malignancy

   • Geoffrey J. Clark, Channing J. Der

   Pages 17-52

4. C-myc as a Tumor Marker for Primary Human Cancers

   • Taro Shuin

   Pages 53-76

5. p53 in Human Cancer

   • Jeffrey R. Marks, Andrew M. Davidoff, J. Dirk Iglehart

   Pages 77-110

6. Oncogenes and Tumor-Suppressor Genes in Gynecological Malignancies

   • Hironobu Sasano, Kiyoshi Ito, Carleton T. Garrett

   Pages 111-138

7. Genetic Alterations in Colon Cancer

   • Suhail Nasim, Carleton T. Garrett

   Pages 139-189

8. Genetic Changes in Breast Cancer

   • Daniel S. Liscia, Tiziana Venesio, Amelia Bernardi, Alberto P. M. Cappa, Robert Callahan

   Pages 191-208

9. Genetic Alterations in Lung Cancer

   • Stephen J. Lemon, Anita L. Sabichi, Michael J. Birrer

   Pages 209-229

10. Wilms Tumor-Susceptibility Loci

    • Vicki Huff

    Pages 231-255

11. Non-Hodgkin’s Lymphomas

    • H.-J. Schuurman, S. C. Henzen-Logmans, Ph. M. Kluin

    Pages 257-288

12. Phenotypic Expression of Hodgkin’s Disease

    • Su-Ming Hsu, Pei-Ling Hsu

    Pages 289-334

13. Melanoma Markers

    • Paul B. Googe, Martin C. Mihm Jr.

    Pages 335-350

14. Detection of Minimal Residual Disease (MRD) in Leukemia and Lymphoma

    • Jonathan M. Ben-Ezra

    Pages 351-374

15. P-Glycoproteins in Tumors

    • William T. Bellamy, Thomas M. Grogan, Ronald S. Weinstein

    Pages 375-391

16. Genetically Engineered Antitumor Monoclonal Antibodies

    • S. V. S. Kashmiri, Patricia Horan Hand

    Pages 393-432

17. Targeting Antisense Oligonucleotide Chemotherapy to the Type I Regulatory Subunit of cAMP-Dependent Protein Kinase

    • Yoon Sang Cho-Chung

    Pages 433-454

18. Summary and Perspective

    • Carleton T. Garrett, Stewart Sell

    Pages 455-477

19. Back Matter

    Pages 479-484

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In Cellular Cancer Markers leading pathologists and physicians review today's most promising cellular cancer markers, an important emerging class of prognostic markers that can be used in the clinical evaluation of cancer patients. The markers reviewed have been chosen because they are biologically relevant to the growth of cells and possess an accurate and reproducible assay for detection. They also are predictors of tumor behavior, are useful in making clinical decisions, and are cost effective.

Cellular Cancer Markers provides a status report for markers of tumor cell activation, proliferation, and longevity that makes possible an informed judgment regarding the value of many newly proposed tumor markers. It also offers insight into the latest approaches to diagnosing cancer and an appreciation of how these marker-based tests can clarify the prognosis of cancer.

• antibody
• cancer
• cell
• leukemia
• lymphoma
• melanoma
• protein
• proteins
• tumor

The editors should be commended for attempting an extensive compilation of information on cancer markers...-New England Journal of Medicine

• Department of Pathology, Medical College of Virginia, Richmond, USA

  Carleton T. Garrett

• Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, USA

  Stewart Sell

Policies and ethics