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Medicine - Pathology | Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice

Leonard, Debra G.B. (Ed.)

2007, XX, 600 p.

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Molecular Pathology in Clinical Practice addresses all areas of molecular pathology clinical practice in a single text, including: molecular biology basics, genetics, infectious diseases, hematopathology, solid tumors, HLA typing, identity testing and laboratory management. This text will provide a comprehensive reference for molecular pathologists as well as the practicing molecular pathologist and trainees. Includes 189 illustrations, 45 in color.

Debra G.B. Leonard, MD, PhD is Professor and Vice Chair of Laboratory Medicine, Department of Pathology and Laboratory Medicine at Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY.

 

Content Level » Professional/practitioner

Keywords » Carcinom - DNA - Microarray - Molecular Pathology - Neurofibromatose - genetics - molecular biology

Related subjects » Human Genetics - Oncology & Hematology - Pathology

Table of contents 

Basics of Molecular Biology.- Basics of Molecular Biology.- Molecular Pathology Methods.- Molecular Pathology Methods.- Genetics.- Genetic Counseling.- Pedigree Analysis and Risk Assessment.- Bayesian Analysis.- Developmental Disabilities.- Neuromuscular Diseases.- Molecular Genetic Testing for Metabolic Disorders.- Fibroblast Growth Factor Receptor-Related Skeletal Disorders.- Cystic Fibrosis.- Deafness.- Coagulation Disorders.- Hematologic Disorders: Hemochromatosis, Hemoglobinopathies, and Rh Incompatibility.- Cardiovascular Disease.- Neurodegenerative Disorders.- Skin and Connective Tissue Disorders.- Inherited Cancers.- Inherited Breast Cancer.- Familial Adenomatous Polyposis and Turcot and Peutz-Jeghers Syndromes.- Hereditary Nonpolyposis Colorectal Cancer.- Multiple Endocrine Neoplasia Syndromes.- The Neurofibromatoses.- TP53 Mutation and Li-Fraumeni Syndrome.- von Hippel-Lindau Disease.- Solid Tumors.- Breast Cancer.- Urothelial Carcinoma.- Sarcomas.- Gliomas.- Molecular Detection of Occult Tumor Cells.- Microarray Studies (Beyond Histology).- Neoplastic Hematopathology.- Acute Myeloid Leukemia.- Acute Lymphoblastic Leukemia.- B-Cell Lymphomas.- T-Cell Lymphomas.- Lymphoproliferations of Immunodeficiency.- Myeloproliferative Disorders and Myelodysplastic Syndromes.- Infectious Diseases.- Human Immunodeficiency Virus Type 1.- Hepatitis B and C Viruses.- Viral Infections in Transplant Patients.- Viral Infections of the Central Nervous System.- Sexually Transmitted Diseases.- Respiratory Pathogens.- Bacterial Pathogens.- Mycobacterial Infections.- Identity Testing.- Forensic DNA Typing.- Parentage and Relationship Testing.- Assessment of Chimerism in the Setting of Allogeneic Hematopoietic Cell Transplantation.- Specimen Identification Through DNA Analysis.- HLA Typing.- Molecular HLA Typing.- Laboratory Management Issues.- Molecular Pathology Laboratory Management.- From Research to Clinical Practice.

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